目的:探討開顱夾閉和血管內栓塞治療顱內動脈瘤的效果比較及并發癥。方法:從2003～2008年近五年來我院收治的顱內動脈瘤54例,其中開顱夾閉24例(Hunt Hess分級Ⅰ～Ⅱ級20例,Ⅲ級2例,Ⅳ級2例),共26個動脈瘤。血管內栓塞30例(HuntHess分級Ⅰ～Ⅱ級23例,Ⅲ級5例,Ⅳ級2例),共31個動脈瘤。臨床結果按GOS進行評價。結果:兩組的良好率、并發癥及死亡率無顯著差別(P gt;0.05)。隨訪平均12月,Ⅰ～Ⅱ級動脈瘤患者治療良好率為100.0％(43/43),并發癥發生率為4.7％(2/43),Ⅲ～Ⅳ級者分別為18.2％(2/11)和90.9％(10/11),兩者相差顯著(P lt;0.05)。結論:開顱夾閉和血管內栓塞治療顱內動脈瘤,二者療效相仿,各有優缺點。動脈瘤患者病情級別越高,治療效果越差。
Citation：
YU Deming,LIU Shengjun,DING Changyun.. Comparison of Effects and Complications between Craniotomy Clipping and Endovascular Embolization in the Treatment of Intracranial Aneurysms. West China Medical Journal, 2009, 24(6): 1481-1483. doi:
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- 1. CHICOINE M R. Microsurgery and clipping: the gold standard for the treatment of intracranial aneurysms[J]. J Neurosurg Anesthesiol,2003,15(1):61-63.
- 2. MORALES F, MAILLO A, HERNANDEZ J, et al. Evaluation of microsurgical treatment in a series of intracranial aneurysms[J]. Neurochirurgia (Austr),2003,14(1):5-15.
- 3. THORNTON J， BASHIR Q， ALETICH V A, et al. What percentage of surgically clipped intracranial aneurysms have residual necks?[J]Neurosurgery,2000,46(6):1294-1298. .
- 4. 程美雄,謝曉東,王朝華,等.Neuroform支架結合彈簧圈治療顱內復雜動脈瘤[J].華西醫學,2009,24(1):148-150.
- 5. 王新,黃正松,曾進勝,等.顱內動脈GDC栓塞治療并發的缺血性腦損害[J].中風與神經疾病雜志,2004,21(2):152-154.
