The Application of 18F-FDG PET/CT in Head and Neck Neoplasms_West China Medical Journal

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1PET Center; 2the Department of Radiation Oncology, Chengdu Army General Hospital, Chengdu 610083, China;

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Keywords：

PET/CT; 頭頸部腫瘤; 放射治療

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目的:探討18F-FDG PET/CT在頭頸部腫瘤的臨床應用價值。方法:58例頭頸部惡性腫瘤病例,男37例,女21例,年齡21~78歲。其中:牙齦癌3例,上頜竇癌2例,舌癌2例,腮腺癌1例,鼻咽癌24例,喉癌8例,甲狀腺癌4例,原發灶不明的頸部淋巴結轉移瘤14例。使用18F-FDG行全身PET/CT掃描,依據PET圖像、CT圖像和PET/CT融合圖像及標準化攝取值(SUV)進行綜合評價。結果:29例放療患者中的11例擬行根治性放療的患者,有4例改行姑息性放療,8例重新勾畫了放療靶區及調整了放療劑量,3例改行其它治療;15例進行了放療后的療效評估;14例原發灶不明的頸部淋巴結轉移瘤8例找到了原發灶。結論:PET/CT可以對頭頸部惡性腫瘤進行準確的臨床分期,精確勾畫放療的生物靶區,準確而快捷地確定腫瘤復發的位置與侵犯范圍,在頸部不明原發灶轉移瘤的應用中具有簡便、快捷、無創和靈敏等臨床特點。

Citation： ZHOU Ke,LUO Jianhua,CHEN Zhiming,et al. The Application of 18F-FDG PET/CT in Head and Neck Neoplasms. West China Medical Journal, 2009, 24(6): 1490-1492. doi: Copy

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1. 潘中允.PET/CT診斷學[M].北京:人民衛生出版社,2009:1;615-629.
2. SHODER H, YEUNG H W D, GONEN M, et al. Head and neck cancer: clinical usefulness and accuracy of PET/CT image fusion[J]. Radiology,2004,231:65-72.
3. DIZENDORF E V, BOUMER B G, VON SCHULTHESS G K, et al. Impact of wholebody 18FFDG PET on staging and managing patients for radiation therapy[J]. J Nucl Med,2002,44:24-29.
4. CIERNIK I F, DIZERDORF E, BOUMENT B G, et al. Radiation treatment planning with on integrated position emission and computed tomography (PET/CT): a feasibility study[J]. Int J Radiat Oncol Biol Phys,2003,57:853-863.
5. DIZENDORF E. Impact biologic target volumes in radiation treatment planning[J]. J Nucl Med,2002,(435):A-118.
6. GREVEN K M, WILLIAMS D W, KEYES J W, et al. Distinguishing tumor recurrence from irradiation sequel as with positron emission tomography in patients treated for larynx cancer[J]. Int J Radiat Oncol Biolphys,1994,29:841-845.
7. NARESH K N. Do metastatic tumours from an unknown primary angiugemic incompetence of the tumour at primary site? A hypotheses[J]. Med Hypotheses,2002,3:357.
8. ALBERINI J L， BELHOCINE T, HUSTINX R, et al. Whole body positron emission tomography using fluoride OXY glucose in patients with metastases of unknown tunours (CPU syndrome)[J]. Nucl Med Commun,2003,10:1081.
9. DELGADO BULTON RC, FEMADEZ C, CNORZAL MATE A, et al. Meta analysis of the performance of 18FFDG PET in primary tumor detection in unknow primary tumors[J]. J Nucl Med,2000,5:816.

West China Medical Journal

The Application of 18F-FDG PET/CT in Head and Neck Neoplasms

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