腹膜透析相關性腹膜炎致病菌的耐藥性分析_West China Medical Journal

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唐勇 , 劉婕

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Keywords：

腹膜透析; 腹膜炎; 抗生素; 抗藥性

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目的:探討腹膜透析相關性腹膜炎的致病菌及其耐藥性。方法:回顧性分析的93例腹膜透析相關性腹膜炎的致病菌及其耐藥性。結果:34例培養陽性, 透出液培養陽性率為36.6%, 其中革蘭陽性球菌14例, 革蘭陰性桿菌17例, 真菌4例。革蘭陰性桿菌對氨芐西林的耐藥率最高,達83.3%,亞胺培南耐藥性最低,達20.0%。革蘭陽性球菌對青霉素、環丙沙星的耐藥率高,分別為81.8%、71.4%。結論:提高腹膜透析液細菌培養陽性率有助于腹膜透析相關性腹膜炎的治療;在經驗用藥基礎上,應依據細菌培養、藥敏,選擇治療腹膜透析相關性腹膜炎的敏感、有效抗菌素,真菌性腹膜炎治療效果仍差,應盡早拔管。

Citation： 唐勇,劉婕. 腹膜透析相關性腹膜炎致病菌的耐藥性分析. West China Medical Journal, 2009, 24(8): 2150-2151. doi: Copy

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7.	郭群英, 陳林, 陽曉, 等. 腹膜透析相關感染性腹膜炎致病菌及菌譜變化單個腹膜透析中心15年回顧分析[J]. 中華腎臟病雜志,2006(12):719-724.
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1. PIRAINO B, BAILIE G R, BERNARDINI J, et al. Peritoneal dialysisrelated infections recommendations: 2005 update[J]. Perit Dial Int,2005,25(2):107-131.
2. FRIED L F, BERNARDINI J, JOHNSTON J R, et al. Peritonitis influences mortality in peritoneal dialysis patients.[J]. J Am Soc Nephrol,1996,7(10):2176-2182.
3. WIGGINS K J, JOHNSON D W, CRAIG J C, et al. Treatment of peritoneal dialysisassociated peritonitis: a systematic review of randomized controlled trials.[J]. Am J Kidney Dis,2007,50(6):967-988.
4. 董捷. 關于2005年ISPD腹膜透析相關感染診治指南的幾點思考[J]. 中國血液凈化,2008(03):117-119.
5. SZETO C C, CHOW K M, KWAN B C, et al. Staphylococcus aureus peritonitis complicates peritoneal dialysis: review of 245 consecutive cases.[J]. Clin J Am Soc Nephrol,2007,2(2):245251.
6. PORT F K, HELD P J, NOLPH K D, et al. Risk of peritonitis and technique failure by CAPD connection technique: a national study.[J]. Kidney Int,1992,42(4):967-974.
7. 郭群英, 陳林, 陽曉, 等. 腹膜透析相關感染性腹膜炎致病菌及菌譜變化單個腹膜透析中心15年回顧分析[J]. 中華腎臟病雜志,2006(12):719-724.
8. KRISHNAN M, THODIS E, IKONOMOPOULOS D, et al. Predictors of outcome following bacterial peritonitis in peritoneal dialysis.[J]. Perit Dial Int,2002,22(5):573-581.

West China Medical Journal

腹膜透析相關性腹膜炎致病菌的耐藥性分析

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