Study on Sevoflurane Anesthesia for Pediatric Patients with Congenital Heart Disease_West China Medical Journal

Authors：

Department of Anesthesiology, Sichuan Provincial People’s Hospital, Chengdu Sichuan 610072, China;

Corresponding?author：

Keywords：

七氟醚; 全憑靜脈麻醉; 先天性心臟病手術

Video：

Export PDF Favorites Scan Get Citation

Abstract Full text Figures/Tables Video References Cited by

目的:觀察、比較七氟醚吸入麻醉與全憑靜脈麻醉在小兒先天性心臟病手術中的應用。方法: 40例擇期行先天性心臟病房室缺矯治術患兒,隨機分為七氟醚組和全憑靜脈麻醉組(TIVA組),每組各20例。七氟醚組患兒以七氟醚吸入誘導,復合小劑量芬太尼、咪達唑侖、維庫溴銨,麻醉維持為七氟醚吸入+芬太尼、維庫溴銨;靜脈組患兒肌注氯胺酮后,以芬太尼、咪達唑侖、維庫溴銨誘導,維持使用丙泊酚持續泵入+芬太尼、維庫溴銨。比較兩組術中各時點血流動力學變化、手術麻醉時間與芬太尼、維庫溴銨用量、術后呼吸支持時間、清醒時間、拔管時間,比較兩組不良反應發生情況。結果: 兩組患兒均維持比較穩定的血流動力學狀態。七氟醚組芬太尼與維庫溴銨用量明顯低于TIVA組,呼吸支持時間、清醒時間、拔管時間明顯低于TIVA組。七氟醚組2例術后發生躁動,3例發生惡心,稍高于TIVA組。結論: 七氟醚應用于小兒先心房室缺矯治術,可提供穩定的血流動力學狀態,并降低芬太尼與肌松劑用量,實現術后早拔管、改善患者預后、降低醫療費用。

Citation： HUANG Jianxin,WANG Yu,LAN Zhixun,et al. Study on Sevoflurane Anesthesia for Pediatric Patients with Congenital Heart Disease. West China Medical Journal, 2009, 24(9): 2290-2292. doi: Copy

1.	MUTO R, MIYASAKA K, TAKATA M, et al. Initial experience of complete switchover to sevoflurane in 1550 children[J]. Paediatric Anaesthesia, 1993, 3 (1): 229.
2.	MuziM, Robinson BJ, Ebert TJ, et al. Induction of anesthesia andtracheal intubation with sevoflurane in adults[J]. Anesthesiology,1996, 85 (3): 5362543.
3.	MELLON RD, SIMONE AF, RAPPAPORT BA. Use of anesthetic agents in neonates and young children. Anesth Analg, 2007,104(3):509-20.
4.	俞衛鋒. 麻醉與復蘇新論[M]. 上海: 第二軍醫大學出版社, 2001: 81-95.
5.	WEI LX, DENG XM, LIU JH. Inductions and intubating conditions with sevoflurane and different doses of remifentanil without muscle relaxant in children[J]. Zhongguo Yi Xue Ke Xue Yuan Xue Bao, 2008,30(6):723-7.
6.	王庚. 安氟醚、七氟醚對維庫溴銨肌松作用的影響[J]. 中華麻醉學雜志, 1997, 17 (6): 342-344.
7.	GAUGER PG, SHANKS A, MORRIS M. Propofol decreases early postoperative nausea and vomiting in patients undergoing thyroid and parathyroid operations[J]. World J Surg, 2008,32(7):1525-34.

1. MUTO R, MIYASAKA K, TAKATA M, et al. Initial experience of complete switchover to sevoflurane in 1550 children[J]. Paediatric Anaesthesia, 1993, 3 (1): 229.
2. MuziM, Robinson BJ, Ebert TJ, et al. Induction of anesthesia andtracheal intubation with sevoflurane in adults[J]. Anesthesiology,1996, 85 (3): 5362543.
3. MELLON RD, SIMONE AF, RAPPAPORT BA. Use of anesthetic agents in neonates and young children. Anesth Analg, 2007,104(3):509-20.
4. 俞衛鋒. 麻醉與復蘇新論[M]. 上海: 第二軍醫大學出版社, 2001: 81-95.
5. WEI LX, DENG XM, LIU JH. Inductions and intubating conditions with sevoflurane and different doses of remifentanil without muscle relaxant in children[J]. Zhongguo Yi Xue Ke Xue Yuan Xue Bao, 2008,30(6):723-7.
6. 王庚. 安氟醚、七氟醚對維庫溴銨肌松作用的影響[J]. 中華麻醉學雜志, 1997, 17 (6): 342-344.
7. GAUGER PG, SHANKS A, MORRIS M. Propofol decreases early postoperative nausea and vomiting in patients undergoing thyroid and parathyroid operations[J]. World J Surg, 2008,32(7):1525-34.

West China Medical Journal

Study on Sevoflurane Anesthesia for Pediatric Patients with Congenital Heart Disease

Abstract Full text Figures/Tables Video References Cited by

Format

Content