Laparoscopic Resection of Splenomegaly for Hereditary Spherocytosis (Report of 18 Cases)_CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

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吳鈞 , 張平 , 王蒙 , 杜曉宏

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遺傳性球形紅細胞增多癥; 腹腔鏡脾切除術; 治療; 二級脾蒂Ligasure兩步離斷

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目的探討腹腔鏡脾切除術治療遺傳性球形紅細胞增多癥的可行性、手術技巧及效果評價。方法收集我科2006年1月至2008年1月收治的行腹腔鏡脾切除術治療的遺傳性球形紅細胞增多癥患者18例的臨床資料進行回顧性分析。結果所有患者均順利完成腹腔鏡脾切除術。術中出血50～600 ml，平均200 ml。手術時間50～150 min，平均136 min（包括膽囊切除時間）。術后住院時間5～10 d，平均7.8 d,所有患者住院期間無暴發感染、胰漏等并發癥發生。術后隨訪4～12個月，平均6.7個月，術前癥狀完全消失。結論腹腔鏡脾切除術是治療遺傳性球形紅細胞增多癥的一種安全有效的方法。

Citation： 吳鈞,張平,王蒙,杜曉宏. Laparoscopic Resection of Splenomegaly for Hereditary Spherocytosis (Report of 18 Cases). CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2009, 16(11): 928-929. doi: Copy

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11.	Poulin EC, Thibault C. The anatomical basis for laparoscopic splenectomy [Ｊ]. Can J Surg, 1993; 36(5): 484-488.
12.	李春林, 彭兵, 李波. 微創外科技術在脾臟相關疾病中的應用 [Ｊ]. 中國普外基礎與臨床雜志, 2008; 15(10): 784-786.
13.	Minkes RK, Lagzdins M, Langer JC. Laparoscopic versus open splenectomy in children [Ｊ]. J Pediatr Surg, 2000; 35(5): 699-701.

1. 張碧紅, 陳純, 岑丹陽, 等. 遺傳性球形紅細胞增多癥26例 [Ｊ]. 實用兒科臨床雜志, 2008; 23(15): 1162-1164.
2. Reddy VS, Phan HH, O’Neill JA, et al. Laparoscopic versus open splenectomy in the pediatric population: a contemporary single-center experience [Ｊ]. Am Surg, 2001; 67(9): 859-864.
3. Friedman RL, Fallas MJ, Carroll BJ, et al. Laparoscopic sp-lenectomy for ITP. The gold standard [Ｊ]. Surg Endosc, 1996; 10(10): 991-995.
4. Kucuk C, Sozuer E, Ok E, et al. Laparoscopic versus open splenectomy in the management of benign and malign hematologic diseases: a ten-year single-center experience [Ｊ]. J Laparoendosc Adv Surg Tech A, 2005; (2): 135-139.
5. 邱曉紅，吳萍，王燕霞，等．脾切除術在遺傳性球形紅細胞增多癥中的應用 [Ｊ]. 中華小兒外科雜志, 2002; 23(3): 210.
6. 錢林生主編. 貧血[M]. 第1版. 北京: 科學出版社， 2004: 28-29.
7. 鄭璐, 李靖, 梁平. 腹腔鏡脾切除術的研究進展 [Ｊ]. 中國普外基礎與臨床雜志, 2005; 12(6): 574-576.
8. Rege RV, Merriam LT, Joehl RJ. Laparoscopic splenectomy [Ｊ]. Surg Clin North Am, 1996; 76(3): 459-468.
9. Hashizume M, Ohta M, Kishihara F, et al. Laparoscopic sp-lenectomy for idiopathic thrombocytopenic purpura: comparison of laparoscopic surgery and conventional open surgery [Ｊ]. Surg Laparosc Endosc, 1996; 6(2): 129-135.
10. Katkhouda N, Hurwitz MB, Rivera RT, et al. Laparoscopic splenectomy: outcome and efficacy in 103 consecutive patients [Ｊ]. Ann Surg, 1998; 228(4): 568-578.
11. Poulin EC, Thibault C. The anatomical basis for laparoscopic splenectomy [Ｊ]. Can J Surg, 1993; 36(5): 484-488.
12. 李春林, 彭兵, 李波. 微創外科技術在脾臟相關疾病中的應用 [Ｊ]. 中國普外基礎與臨床雜志, 2008; 15(10): 784-786.
13. Minkes RK, Lagzdins M, Langer JC. Laparoscopic versus open splenectomy in children [Ｊ]. J Pediatr Surg, 2000; 35(5): 699-701.

CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

Laparoscopic Resection of Splenomegaly for Hereditary Spherocytosis (Report of 18 Cases)

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