Simultaneous Pancreas-Kidney Transplantation （Report of One Case )_CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

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田伯樂 , 張肇達 , 劉續寶 , 胡偉明 , 韓方海 , 麥剛 , 趙紀春 , 王莉 , 陸慧敏 , 任燕 , 羅朝志 , 羅傳興 , 袁朝新 , 陸燕蓉

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胰腺,腎,移植

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【摘要】目的報道四川大學華西醫院首例胰腎聯合移植。方法 2007年3月我院對1例2型糖尿病合并腎功能衰竭患者成功施行了胰腎聯合移植手術，將腎臟移植于左側髂窩，胰腺移植于右側髂窩，胰腺移植采用腸道-體循環回流術式。結果術后第1 d C-肽升至正常水平，第4 d血肌酐恢復正常，第11 d血尿素氮恢復正常，血糖逐漸趨于穩定，第16 d完全停用胰島素，術后3周OGTT結果顯示移植胰腺功能正常。隨訪6個月移植胰腺、腎臟功能正常，沒有發生手術相關并發癥。
結論胰腎聯合移植是治療2型糖尿病合并腎功能衰竭的有效手段。

Citation： 田伯樂,張肇達,劉續寶,胡偉明,韓方海,麥剛,趙紀春,王莉,陸慧敏,任燕,羅朝志,羅傳興,袁朝新,陸燕蓉. Simultaneous Pancreas-Kidney Transplantation （Report of One Case ). CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2008, 15(3): 203-204. doi: Copy

1.	9 Ki Wan K, Rick S, Rod M, et al. Simultaneous kidney-pancreas transplantation (SPK) for type 2 diabetes mellitus: Single center experience [Ｊ] . Am J Transplant, 2007; 7 Suppl 2 ∶ 250.
2.	明長生, 甑忠廣, 曾凡軍, 等. 32例胰腎同期聯合移植的近期療效 [Ｊ].　中華器官移植雜志,　2006; 27(1)∶36.
3.	Troppmann C, Benedetti E, Papalois BE, et al. Impact of vascular reconstruction technique on posttransplant pancreas graft thrombosis incidence after simultaneous pancreas-kidney transplantation [Ｊ].Transplant Proc, 1995; 27(1)∶1331.
4.	Reddy KS, Johnston TD, Karounas D, et al. Hospital charges following simultaneous kidney-pancreas transplantation: enteric drainage versus bladder drainage [Ｊ]. Clin Transplant, 2000; 14(4 Pt 2)∶375.
5.	明長生. 臨床胰腺和胰腎聯合移植的現狀 [Ｊ]. 中華器官移植雜志, 2006; 27（11）∶699.
6.	Schmied BM, Müller SA, Mehrabi A, et al. Immunosuppressive standards in simultaneous kidney-pancreas transplantation [Ｊ].Clin Transplant, 2006; 20 Suppl 17∶44.
7.	黃東勝, 徐驍. 胰腎聯合移植的指征和現狀 [Ｊ]. 中國普外基礎與臨床雜志, 2003; 10（6）∶528.
8.	Gruessner AC, Sutherland DE. Pancreas transplant outcomes for United States (US) and non-US cases as reported to the United Network for Organ Sharing (UNOS) and the International Pancreas Transplant Registry (IPTR) as of June 2004 [Ｊ]. Clin Transplant, 2005; 19(4)∶433.
9.	Nath DS, Gruessner AC, Kandaswamy R, et al. Outcomes of pancreas transplants for patients with type 2 diabetes mellitus [Ｊ]. Clin Transplant, 2005; 19(6)∶792.

1. 9 Ki Wan K, Rick S, Rod M, et al. Simultaneous kidney-pancreas transplantation (SPK) for type 2 diabetes mellitus: Single center experience [Ｊ] . Am J Transplant, 2007; 7 Suppl 2 ∶ 250.
2. 明長生, 甑忠廣, 曾凡軍, 等. 32例胰腎同期聯合移植的近期療效 [Ｊ].　中華器官移植雜志,　2006; 27(1)∶36.
3. Troppmann C, Benedetti E, Papalois BE, et al. Impact of vascular reconstruction technique on posttransplant pancreas graft thrombosis incidence after simultaneous pancreas-kidney transplantation [Ｊ].Transplant Proc, 1995; 27(1)∶1331.
4. Reddy KS, Johnston TD, Karounas D, et al. Hospital charges following simultaneous kidney-pancreas transplantation: enteric drainage versus bladder drainage [Ｊ]. Clin Transplant, 2000; 14(4 Pt 2)∶375.
5. 明長生. 臨床胰腺和胰腎聯合移植的現狀 [Ｊ]. 中華器官移植雜志, 2006; 27（11）∶699.
6. Schmied BM, Müller SA, Mehrabi A, et al. Immunosuppressive standards in simultaneous kidney-pancreas transplantation [Ｊ].Clin Transplant, 2006; 20 Suppl 17∶44.
7. 黃東勝, 徐驍. 胰腎聯合移植的指征和現狀 [Ｊ]. 中國普外基礎與臨床雜志, 2003; 10（6）∶528.
8. Gruessner AC, Sutherland DE. Pancreas transplant outcomes for United States (US) and non-US cases as reported to the United Network for Organ Sharing (UNOS) and the International Pancreas Transplant Registry (IPTR) as of June 2004 [Ｊ]. Clin Transplant, 2005; 19(4)∶433.
9. Nath DS, Gruessner AC, Kandaswamy R, et al. Outcomes of pancreas transplants for patients with type 2 diabetes mellitus [Ｊ]. Clin Transplant, 2005; 19(6)∶792.

CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

Simultaneous Pancreas-Kidney Transplantation （Report of One Case )

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