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Corticosteroids Combined With Cyclosporine for Penetrating Keratoplasty Recipients: A MetaAnalysis

目的:評價皮質激素聯合環孢素對比皮質激素單用防治穿透性角膜移植(PKP)術后排斥反應的療效。方法:計算機檢索PubMed,EMBASE.com,SCI,Cochrane圖書館,CBM,CNKI數據庫,納入皮質激素聯用環孢素對比皮質激素單用防治PKP術后排斥反應的隨機對照試驗,進行方法學質量評價并應用RevMan軟件進行meta分析。結果:共納入5篇報道,1篇A級文獻,B、C級各2篇。Meta結果:術后排斥反應發生情況組間差異有統計學意義(RR=0.3,95%CI 0.140.65);對既發排斥反應的逆轉,組間差異無統計學意義(RR=1.15,95%CI 0.93-1.42)。結論:基于當前證據,皮質激素聯合環孢素防治PKP術后排斥反應療效并不優于皮質激素單用。

Retrospective Analysis of the Causes of Death and Its Clinical Data in 149 of Dead Inpatients with Diabetic Nephropathy

The Relationship between Pathological Feature of Liver Biopsies and Serological Markers of Bhepatitis in Patients with Chronic Asymptomatic Hepatitis B Carrier

摘要:目的:分析慢性乙肝病毒攜帶者肝組織病理與年齡、病程、血清學及肝臟免疫組化指標的相關性,以確定孰是對病理進程影響最主要的指標。方法:對134例臨床診斷的慢性乙肝病毒攜帶者進行乙肝血清學標志物、肝功能、肝活組織病理及免疫組化的檢查。結果:①病理表現為不典型增生者HBeAg陰性組少于HBeAg陽性組,而表現為慢性肝炎者前者多于后者,差異均有顯著性;HBVDNAlt;105亞組分析兩組病理表現無統計學差異;兩種病理表現類型在年齡18~40歲組及gt;40歲組明顯多于lt;18歲,差異均有顯著性;兩種病理類型在免疫組化雙陽性組均多于單陽性組及全陰

Efficiency Analysis of Somatostatin for the Treatment of Peptic Ulcer Complicated by Upper Gastrointestinal Bleeding

目的:比較國產生長抑素與進口生長抑素治療消化性潰瘍出血的經濟效果。方法:將120例消化性潰瘍伴出血的患者隨機分成國產生長抑素及進口生長抑素組,分別給予國產生長抑素、進口生長抑素治療3天,觀察療效,并進行藥物經濟學評價。 結果: 國產生長抑素、進口生長抑素治療上消化道出血成本分別為558元和4116元,有統計學差異(P＜005);有效率分別為925%和968%,無統計學差異 (Pgt;005),成本—效果比分別為60324和425207,有統計學差異(P＜005)。結論: 從藥物經濟學角度分析,國產生長抑素治療消化性潰瘍出血較進口生長抑素更為經濟。

Retrospective Analysis of the Emergency Response Capacity of the Zigong Urgent Rescue Center in PreHospital Care in the Year of 2007

目的:通過分析2007年自貢市急救中心院前急救反應能力，探討其影響制約因素及解決方法。方法：回顧性分析2007年1～12月份自貢市急救中心院前出診的全部有效病例呼救時間、出車時間、到達現場時間及出診距離，計算出車準備時間、車輛行駛速度、應急反應時間、急救半徑。結果：全年院前出診共3336例，出車準備時間（2.06±0.93） min，車輛平均行駛速度32.17 km/h，應急反應時間（12.51±10.87） min，急救半徑（5.60±5.35） km。結論：我市急救中心目前取得一定成績，需采取多種措施進一步提高急救反應能力。

The Relationship between Microalbuminuria and Coronary Artery Disease

摘要:目的: 研究尿微量白蛋白與冠心病的相關性。 方法 : 按冠狀動脈造影診斷標準將116例患者分為冠心病組(82人) 與非冠心病組(34人),測定晨尿白蛋白/ 肌酐濃度值(ACR),比較兩組患者尿ACR 并分析ACR與冠脈病變程度的相關性。 結果 : 冠心病組ACR顯著高于非冠心病組的; ACR與冠脈計分呈顯著的直線正相關。 結論 :冠心病患者ACR水平升高,微量白蛋白尿與冠狀動脈病變范圍和程度密切相關, 且對冠狀動脈狹窄程度具有獨立預測價值。Abstract: Objective: To investigate the relationship between microalbuminuria and coronary artery disease(CAD). Methods : According to the diagnostic standard of coronary artery angiography,116 patients were divided into CAD group (82 patients) and nonCAD group (34 patients). The albumin and creatinine concentrationratio ratio(ACR) in morning urine samples from patients of both groups was estimated and compared. The correlation of ACR to the extent of coronary lesions was analyzed. Results : ACR in the CAD group was significantly higher than that in nonCAD group. A distinctly linear positive correlation existed between ACR and the score of the coronary lesions. Conclusion : ACR increase in patients with CHD.Micoalbuminuria was associated with the severity of coronary lesions in patients with CHD and is an independent predictor of CAD.

Analysis of Adverse Drug Reaction of Glucoside Tripterygium Total

目的:減少雷公藤多苷片引起的嚴重不良反應發生,保證用藥安全。方法:通過檢索雷公藤多苷片不良反應相關文獻,篩選個案或典型病例報告,分析該類不良反應的臨床特征。結果:64例個案病例中,不良反應累及器官或系統以血液系統為主、其次為生殖系統、泌尿系統和肝膽系統,大多較輕微,為一過性,停藥后對癥治療可以恢復,但長期或大劑量服用可能導致嚴重的不良反應。結論:雷公藤多苷片所致不良反應與服藥時間相關,可累積多個系統,建議根據病情嚴格控制服藥劑量,并且在服藥前和服藥期間檢查血、尿常規和肝腎功能。 

CT Findings and Clinical Analysis of Neonatal Hypoxic Ischemic Encephalopathy

摘要:目的:探討新生兒缺氧缺血性腦病(HIE)的CT表現與臨床分析。方法:對54例HIE患兒的CT表現及臨床特點進行回顧性分析。結果:本組臨床分度為輕度21例,占38.9％(21/54);中度24例,占44.4％(24/54);重度9例,占16.7％(9/54)。CT分度為輕度25例,占46.3%(25/54);中度18例,占33.3%(18/54);重度11例,占20.4%(11/54)。結論:CT對明確HIE的范圍、動態觀察病情變化,對臨床早期干預治療,降低后遺癥有積極作用。Abstract: Objective: To explore the neonatal hypoxic ischemic encephalopathy (HIE) of CT findings and clinical analysis.Methods:Children of the 54 cases of HIE and clinical performance characteristics of CT were retrospectively analyzed.Results:Clinical subgroup 21 cases of mild degree, accounting for 38.9% (21/54); 24 cases of moderate, accounting for 44.4% (24/54); 9 cases of severe, accounting for 16.7% (9 / 54). CT at 25 cases of mild degree, accounting for 46.3% (25/54); 18 cases of moderate, accounting for 33.3% (18/54); 11 cases of severe, accounting for 20.4% (11/54).Conclusion:CT of the scope of HIE clear, dynamic observation of the disease changes in the clinical treatment of early intervention to reduce the aftereffects have a positive effect.

An Analysis of 4109 Cases in Prehospital Care by ICD10

摘要:目的: 通過分析地市級急救中心院前急救資料,探討ICD10疾病分類方法在院前急救中的實用性。 方法 :回顧性分析2007年1~12月份自貢市急救中心出診的全部有效急救患者的急診診斷以及隨訪診斷,使用ICD10編碼進行歸類,比較疾病性別構成比。 結果 :全年院前急救4109例,排5位的疾病分別為損傷、中毒和外因的某些其他后果(484%)、循環系統疾病(170%)、消化系統疾病(81%)、呼吸系統疾病(64%)、精神和行為障礙(52%),損傷、中毒和外因的某些其他后果、循環系統疾病以及消化系統疾病出診量男性多于女性(P＜005),耳和乳突疾病以及妊娠、分娩和產褥期疾病出診量女性多于男性(P＜005)。 結論 :采用ICD10標準對院前急救病譜分類有進一步探討的價值。Abstract: Objective: To investigate the value of ICD10 in prehospital care by the analysis of cases in Zigong Urgent Rescue Center. Methods : All cases of prehospital care during the year of 2007 were studied, whose emergency Diagnoses and followup diagnoses were recorded, and they were classified by international classification of diseases 10th revision (ICD10). The gender composition ratio of diseases was analyzed. Results : Four thousand one hundred and nine cases of prehospital care in 2007 were included. Topfive diseases were injury, poisoning and certain other consequences of external causes (484%), diseases of the circulatory system (170%), diseases of the digestive system (81%), diseases of the respiratory system (64%), and mental and behavioral disorders (52%) respectively. The amout of the male prehospital cases was more that of than the female’s in the diseases of injury, poisoning and certain other consequences of external causes, diseases of the circulatory system, diseases of the digestive system (P＜005); the amount of the female prehospital cases was more than that of the male’s in the diseases of the ear and mastoid process, pregnancy, childbirth and the puerperium (P＜005). Conclusion : Further research on the spectrum of diseases classified by ICD10 is valuable.

Clinical Analysis of 228 Cases of Premature Infants

摘要:目的: 探討如何提高早產兒存活率和生存質量。 方法 :對我院新生兒病房收治的228例早產兒的臨床資料進行了回顧分析。 結果 :引起早產的母親因素以胎膜早破、妊娠期膽汁淤積綜合征及妊娠合并高血壓綜合征為早產的重要因素,而引起早產兒常見疾病的是新生兒肺炎,高膽紅素血癥及新生兒窒息等。而呼吸衰竭、新生兒休克、多器官衰竭則是引起早產兒預后不良的重要因素。 結論 :早產原因以母體因素為主,故加強孕期保健,積極防治母親的有關并發癥,同時提高新生兒急救水平,早期干預,以提高早產兒的生存質量。Abstract: Objective: To exploere the ways of promoting the survival rate and the quality of life in premature infants. Methods :The clinical data on 228 cases of premature infants treated by neonatal wards were analyzed retrospectivelly. Results : The important factors of premature are cholestasis of pregnancy syndrome, premature rupture of membbranes, and hypertemsion in prefnancy. The commom diseases in premature infants are neonatal pnecemonia, hyperbilirubinemia and asphxia, the major factors in poor prognasis are caused by neonatal shock, multiple organ failure in premature infants. Conclusion :The main reasons of premature is maternal factors. It is important to strengthen the health care during pregnancy, control the complications of mothers actively, at the same time, improve the level of neonatal first aid, intervent early, so as to imprive the quality of life in preterm infants.