摘要:目的: 探討重癥急性胰腺炎的臨床治療方法。 方法 :回顧性分析我院自19984~20067共收治的各類重癥急性胰腺炎患者56例。 結果 : 治療上采取在內科治療的基礎上,選擇適當手術干預,除2例并發多器官功能衰竭病死外,全部治愈出院。 結論 :重癥急性胰腺炎的處理要根據患者的具體情況,應首先采取非手術治療,并針對不同情況合理選擇外科手術治療。Abstract: Objective: To discussion the clinical treatments of the severe acute pancreatitis. Methods : Retrospective analysis all kinds of the severe acute pancreatitis from 1998420067 in our hospital. Results : The treatments are based on nonsurgical treatment and with the selection of appropriate surgical intervention, all patients have cured except tow cases who died in multiple organ failure. Conclusion : According to the specific circumstances of the patients, The treatments of severe acute pancreatitis should be adopted first nonsurgical treatment, and with a reasonable choice of the surgery for different circumstances.
目的探討在可促進增殖范圍內的壓力加載與膀胱平滑肌細胞損傷的關系。
方法將體外培養的膀胱平滑肌細胞分為實驗組和對照組,實驗組施予40 cm H2O(1 cm H2O=0.098 kPa)壓力加載培養,對照組無壓力加載培養,24 h后觀察細胞形態并采用免疫熒光檢測膀胱平滑肌細胞骨架α-actin及碘化丙啶(PI)染色。
結果實驗組與對照組細胞形態結構無明顯差異;α-actin免疫熒光面積測量實驗組為(50.93±1.99)%,對照組為(24.70±1.61)%,兩組間的表達量差異有統計學意義(t=32.404,P<0.001);PI染色陽性細胞數量實驗組為(9.00±1.41)%,對照組為(3.50±2.12)%,實驗組明顯高于對照組,差異有統計學意義(t=6.110,P<0.001)。
結論壓力加載條件在促進細胞增殖的同時也會對膀胱平滑肌細胞造成損傷。