Search

頻域光相干斷層掃描分層分析及其在眼科疾病中的應用

光相干斷層掃描（OCT）作為一種快速非侵入性和非接觸性的檢查技術，能對視網膜的解剖結構進行高分辨率的重建。OCT分層分析是隨著高分辨率第四代頻域（SD）OCT（SD-OCT）廣泛應用衍生出來的研究疾病的新方法，能夠確定內界膜到Bruch膜之間不同視網膜結構層面的邊界并測量相應層面的視網膜結構厚度或面積。有助于對視網膜病變結構和功能研究深入到更細微層面；對了解相關疾病的發生機制，監測評估及早期診斷將會產生深遠的影響。但目前分層分析方法尚不十分成熟，在臨床或實驗過程中，測量時仍存在一定的誤差和局限性。還需要以科學審慎的態度解讀SD-OCT分層分析的結果，以便客觀正確應用這一技術，推動我們對疾病發生發展過程中不同視網膜層面改變的認識不斷深入。

Krypton laser treatment ofneovascularization in retinal vein occlusion

Objective To investigate the method and effect of krypton laser photocoagulation for neovascularization in retinal vein occlusion . Methods Tweenty eight eyes of 27 patients with retinal vein occlusion with neovascularization were photocoagulated by krypton green and red laser.The fundus changes were observed by fundus fluorescein angiography after photocoagulation. Results The neov ascularization disappeared completely in 20 eyes and became smaller in 6 eyes,re mained no change in 2 eyes,and the visual acuity improved in 17 eyes (60.7%) after 6 monthes to 2.5 years of follow-up. Conclusion Krypton laser photocoagulation is obviously effective on regression of n eovascularization and prevenion of vitreous hemorrhage in retinal vein occlusion . (Chin J Ocul Fundus Dis, 2001,17:12-14)

氬激光眼內探頭眼外引流視網膜下液的臨床觀察

多波長氪激光治療視網膜大動脈瘤的療效觀察

The amount of endothelial progenitor cells at different stages of diabetic retinopathy in patients with type 2 diabetes mellitus

　　Objective　To observe the amount of endothelial progenitor cells (EPCs) at different stages of diabetic retinopathy (DR) in patients with type 2 diabetes mellitus (DM). Methods　Sixty patients with type 2 DM were divided into no DR (NDR) group, non-proliferative DR (NPDR)group and proliferative DR (PDR)group according to the examination of fundus and fundus fluorescein angiography, 20 patients in each group. Twenty healthy people were collected as the control group. 6 ml blood samples were taken from all the subjects, and then the EPCs contents in peripheral blood were detected by flow cytometry. Results 　The EPCs contents in peripheral blood of the control, NDR, NPDR and PDR group were (0.0179plusmn;0.0047)%, (0.0151plusmn;0.0086)%, (0.0123plusmn;0.1137)%, (0.0316plusmn;0.0 294)%. The EPCs contents in peripheral blood of the PDR group was significantly higher than those in others (chi;2=43.780, P＜0.05); the EPCs contents in peripheral blood of the NDR and NPDR group were slightly lower than that in the control group (chi;2=5.244, P=0.73); the EPCs contents in peripheral blood of the NPDR group was lower than that in the NDR group (chi;2=6.016, P=0.12). Conclusion　The EPCs contents in peripheral blood decreases in NDR, NPDR patients, while significantly increases in PDR patients.