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        west china medical publishers
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        find Author "武燕" 2 results
        • 慢性阻塞性肺疾病氣道炎癥的研究進展

          慢性阻塞性肺疾病( COPD) 是一種氣流受限呈不完全可逆和進行性發展狀態的氣道阻塞性肺部疾病, 包括肺氣腫、末梢氣道疾病和慢性支氣管炎。其發病機制尚未完全闡明, 目前普遍認為COPD 以氣道、肺實質和肺血管的慢性炎癥為特征, 在肺的不同部位有肺泡巨噬細胞、T 淋巴細胞和中性粒細胞增加。激活的炎癥細胞釋放多種介質, 包括白三烯B4( LTB4) 、IL-8、TNF-α和其他介質, 導致肺內氧化/ 抗氧化失衡、蛋白酶/ 抗蛋白酶失衡等, 從而破壞肺的結構和促進多種炎癥細胞的炎癥反應。目前, COPD 是世界上第四位的主要死亡原因, 而在我國已居疾病負擔序列的第一位。因此, 深入研究COPD 的發病機制, 探討治療COPD 的有效方法具有重要的理論及實踐意義, 本文對其最新研究進展進行了綜述。

          Release date:2016-09-13 04:06 Export PDF Favorites Scan
        • Summary of best evidence for treatment and management of acute myocardial infarction under the mode of chest pain center

          Objective To search, evaluate and summarize the relevant evidence of the treatment and management of patients with acute myocardial infarction (AMI) under the chest pain center mode by using the evidence-based medicine method, so as to provide references for optimizing the clinical pathway, improving the medical quality and improving the prognosis of patients. Methods Relevant evidence on the treatment and management of AMI patients in relevant databases and websites at home and abroad was retrieved, and the retrieval time limit was from the establishment of databases to January 1, 2025. The quality of the included literature was evaluated, and the evidence was extracted and summarized. Results A total of 15 articles were included, including 2 clinical decisions, 2 systematic reviews, 8 guidelines, and 3 expert consensuses. Finally, 23 pieces of best evidence were extracted, including the basic conditions of chest pain center, the evaluation and treatment of patients with acute chest pain, the integration of pre-hospital emergency system and hospital green channel, and training and education. Conclusions The best evidence for the treatment and management of AMI under the chest pain center mode can provide evidence-based basis for clinical practice. It is necessary to combine the situation of the chest pain center, fully consider the validity and feasibility of the evidence, and help the chest pain center improve the medical quality and improve the prognosis of patients in a standardized and scientific way.

          Release date:2025-10-27 04:22 Export PDF Favorites Scan
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