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        west china medical publishers
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        find Author "沈杰" 2 results
        • RESEARCH PROGRESS OF PERIPHERAL NERVE SURGERY ASSISTED BY Da Vinci ROBOTIC SYSTEM

          ObjectiveTo summarize the research progress of peripheral nerve surgery assisted by Da Vinci robotic system. MethodsThe recent domestic and international articles about peripheral nerve surgery assisted by Da Vinci robotic system were reviewed and summarized. ResultsCompared with conventional microsurgery, peripheral nerve surgery assisted by Da Vinci robotic system has distinctive advantages, such as elimination of physiological tremors and three-dimensional high-resolution vision. It is possible to perform robot assisted limb nerve surgery using either the traditional brachial plexus approach or the mini-invasive approach. ConclusionThe development of Da Vinci robotic system has revealed new perspectives in peripheral nerve surgery. But it has still been at the initial stage, more basic and clinical researches are still needed.

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        • 樹突狀細胞聯合細胞因子誘導殺傷細胞治療晚期惡性腫瘤患者近期臨床療效觀察

          目的觀察研究樹突狀細胞(DC)聯合細胞因子誘導殺傷細胞(CIK)協同治療晚期惡性腫瘤患者的近期臨床療效。 方法采集2013年1月-6月104例晚期惡性腫瘤患者外周血單個核細胞進行DC、CIK細胞培養,7~14 d后回輸患者體內,觀察治療期不良反應癥狀及治療前后免疫指標、生活質量變化情況,并評估治療后病情緩解情況。 結果治療期低熱5例,乏力3例,皮疹1例,無其他任何不良反應癥狀;治療后患者外周血中CD3+、CD4+及自然殺傷細胞百分比上升,CD8+細胞百分比下降,生活質量指標及Karnofsky功能狀態評分均有改善,差異有統計學意義(P<0.05);68例可測量病灶患者治療后部分緩解18例,穩定42例,進展8例,客觀緩解率為26.5%,疾病穩定率為88.2%。 結論DC/CIK細胞免疫治療在殺滅腫瘤細胞的同時,可以修復患者免疫系統,改善患者生活質量,且安全性高,不良反應小,可成為繼手術、放射治療、化學治療后晚期惡性腫瘤治療的重要手段。

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