Pleuropulmonary blastoma (PPB) is a kind of rare malignancy which often occurs in children and is related to dysplasia. It always involves in pleura and lung. PPB is misdiagnosed easily because of its special pathophysiological characters and complex biological behavior. Early detection and correct treatment are very important for thoracic surgeon to cure PPB. This paper reviews the advance of pathophysiological characters, molecular genetic characters, clinical manifestation, clinical diagnosis and differential diagnosis, and treatment and prognosis of PPB.
In order to protect the integrity and function of the digestive system, duodenum-preserving total pancreatic head resection is becoming the surgical method which was chosen by more and more doctors for benign lesions or low-grade malignant tumors of the pancreatic head. With the development of minimally invasive concepts and techniques, laparoscopic technology has brought unique advantages to this surgery. In this paper, a series of problems such as the development process and indications of laparoscopic duodenum-preserving total pancreatic head resection were discussed, and the core techniques of surgery and how to reduce the occurrence of complications were emphasized. The aim is to improve the therapeutic effect and quality of life of patients through reasonable surgical methods and treatment strategies.
ObjectiveThis study summarizes the latest research on the use of inflammatory markers to predict clinically relevant postoperative pancreatic fistula (CR-POPF), and explores the impact of perioperative inflammatory regulation on CR-POPF, providing references for early warning and individualized intervention for CR-POPF. MethodsA systematic review and summary of relevant literature from the past decade on the early prediction and diagnosis of CR-POPF using inflammatory biomarkers. ResultsThe inflammatory cascade triggered by pancreatic surgery plays a significant role in the development and progression of CR-POPF. Numerous studies had confirmed that following pancreatic surgery, inflammatory markers such as interleukin-6 (IL-6), C-reactive protein (CRP), procalcitonin (PCT), inflammatory cells, and other inflammatory markers had significant predictive and diagnostic value for early CR-POPF. Additionally, studies had shown that dynamic monitoring of the trends and magnitude of changes in these inflammatory markers, as well as the establishment of predictive models incorporating inflammatory indicators, could enhance the accuracy of predicting CR-POPF. Furthermore, appropriate anti-inflammatory therapy during the perioperative period plays a positive role in the prevention and treatment of CR-POPF. ConclusionsEarly prediction of CR-POPF is crucial for improving postoperative clinical outcomes and short-term prognosis in patients. Traditional inflammatory markers such as IL-6, CRP and PCT have unique value in the early prediction and diagnosis of CR-POPF. Dynamic monitoring can reflect changes in disease status, thereby influencing clinical management. Future research should further clarify and standardize the predictive timepoints and threshold criteria for inflammatory markers, and explore novel inflammatory markers to provide more accurate and comprehensive guidance for early risk stratification and personalized management of pancreatic fistula in clinical practice.
Objective To investigate the possibility of using extendible distal femoral replacements in the treatment of osteosarcoma in growing individuals. Methods From December 1999 to March 2003, 3 cases (2 were typeⅡB, 1 was type ⅡA) with osteosarcoma were treated byextendible distal femoral replacements. Of the 3 cases, 2 underwent prosthesis extention operation, 1 was not operated. Results After the removal of tumor, the extremities of 2 patients were shortened by 4 to 5 cm within 2 to 3 years. After the lengthening procedure, the affected extremities were of equal length to the unaffected extremities and no drag symptoms of blood vessel and nerves were observed. Follow-up was done for 2 months to 3 years. There was no aseptic loosening. The function of joints was fairly good. Conclusion Extendible distal femoral replacements is an easy, convenient, and effective way to treat osteosarcoma.
Objective To observe the action and correlation of p16 and estrogen receptor (ER) in papillary thyroid cancer (PTC).Methods Using immunohistochemical method, the p16 and ER in 50 cases of PTC were detected. Results The expression of p16 and ER was associated with the cellular differentiation, the lymphatic metastasis and prognosis in PTC. Conclusion It is helpful to detect the p16 protein and ER for analyzing the cellular differentiation degree and prognosis in PTC.
【摘要】 目的 分析國內醫學期刊發表的災害護理文獻，為災害護理證據的生產和傳播提供參考。 方法 檢索中國知網CNKI全文數據庫醫藥衛生專輯（1991~2010.01），收集災害護理相關文獻，進行分類和描述性統計分析。 結果 207篇文獻中，2008年前發表32篇（15.47%），2008年及以后發表175篇（85.53%）。文獻分布于67種醫學期刊，其中護理類17種98篇（47.34%），非護理類50種109篇（52.66%）。統計源期刊137篇（66.18%），其他期刊70篇（33.72%）。護理類統計源期刊收錄79篇，占護理類期刊刊發數的80.61%。以經驗類128篇（61.84%），理論類60篇（28.98%），研究類19篇（9.18%）；內容以醫療救護類94篇（61.84%），管理類 72篇（28.98%），教育類31篇（14.98%），其他類10篇（4.83%）；醫療救護類文獻中，未見慢性病相關文獻。 結論 2008年是災害護理文獻增長的分界點，統計源期刊是證據的主要來源。災害護理文獻以經驗類為主，涵蓋災害醫療救護、管理及教育，需要開發災害慢性病護理證據。【Abstract】 Objective To analyze the literature on disaster nursing published in medical journals and provide reference for the development and dissemination of evidence on disaster nursing. Methods Papers on disaster nursing were get from the CNKI database (1991 to January 2010). After classification, they were inputted to excel and descriptive analysis was applied. Results There were totally 207 papers, among which 32 (15.47%) were published before 2008 and 175 (85.53%) were published in and after 2008. Papers were published in 67 medical journals, for which 17 (98 papers, 47.34%) were nursing Journals, while 50 (109 papers, 52.66%)were not nursing. one hundred and thirty-seren papers (66.18%) were published in Source Journals for Chinese Scientific and Technical Papers and Citations, 70 (33.72%) were not. Seventy-nine papers were published in nursing journals for Chinese Scientific and Technical Papers and Citations. On the type, 128 papers (61.84%) were experience ones, 60 (28.98%) were theoretical papers and 19 (9.18%) were research papers. On the content, 94 (61.84%) were about nursing and rescue practice, 72 (28.98%) were about disaster nursing management, 31 (14.98%) were on disaster nursing education and 10 (4.83%) were others. No literature on chronic disease was found among papers on nursing and rescue practice. Conclusion The year 2008 is apoint for the development of disaster nursing evidence. The evidence were published in kinds of medical journals. The Source Journals for Chinese Scientific and Technical Papers and Citations were the main source for the evidence. The evidence were mainly experience ones. The evidence covered in the fields of nursing and rescue practice, disaster nursing management and disaster nursing education, literature on disaster amp; chronic disease was needed.
ObjectiveTo summary the diagnosis and surgical treatment experiences of posterior collicular fracture of medial malleolus. MethodsBetween March 2008 and November 2010, 14 patients having lateral and (or) posterior malleolus fractures with posterior collicular fracture of medial malleolus were treated with open reduction and internal fixation, including 5 males and 9 females with an average age of 44.5 years (range, 27-60 years). The causes of injuries were strain in 9 cases, traffic accident in 3 cases, and falling from height in 2 cases. The course of fracture ranged from 3 to 9 days (mean, 6.5 days). Fourteen cases were lateral malleolus fractures, 10 cases were posterior malleolus fractures. According to Lauge-Hansen classification, there were 8 cases of pronation-external rotation type, 3 cases of pronation-abduction type, and 3 cases of supination-external rotation type. ResultsAll incisions healed by first intention with no complication. The patients were followed up 12-24 months (mean, 16.8 months). The X-ray films showed that all fractures healed from 2 to 4 months after operation (mean, 2.9 months). The range of motion (ROM) of affected ankles was (38.40 ± 3.50)° of flexion and was (16.30 ± 2.41)° of extension, showing no significant difference when compared with ROM of normal side [(40.50 ± 3.48)° and (17.90 ± 2.28)°, P gt; 0.05]. All patients’ ankle function was evaluated by Olerud-Molander’s score criteria for ankle function evaluation, the results were excellent in 7 cases, good in 6 cases, and fair in 1 case. ConclusionSpiral CT plays an indispensable role in diagnosis of posterior collicular fracture of medial malleolus. Surgical reduction and rigid fixation should be performed.
