目的 對比A型超聲角膜測厚儀、OrbscanⅡ眼前節分析儀和Pentacam眼前節分析儀測量準分子激光原位角膜磨鑲術（LASIK）前后中央角膜厚度的差異。 方法 2010年10月－2011年3月，分別使用A型超聲角膜測厚儀、OrbscanⅡ和Pentacam眼前節分析儀測量137例（274只眼）近視患者LASIK前后中央角膜厚度，并對測量結果進行配對t檢驗和Pearson相關性分析。 結果 LASIK術前A型超聲、OrbscanⅡ和Pentacam測量值分別為（526.6 ± 34.1）、（516.6 ± 34.2）、（539.8 ± 31.5） μm，Pentacam測量值較A型超聲和OrbscanⅡ測量值高，差異有統計學意義（P＜0.05），而A型超聲和OrbscanⅡ測量值之間差異無統計學意義（P＞0.05）；LASIK術后6個月A型超聲、OrbscanⅡ和Pentacam測量值分別為（448.2 ± 48.5）、（391.9 ± 58.5）、（451.5 ± 46.4） μm，LASIK術后A型超聲和Pentacam測量值無差異（P＞0.05），而OrbscanⅡ測量值較A型超聲和Pentacam低；Pearson相關分析顯示，LASIK術后Pentacam和A型超聲CCT測量值呈高度相關（P＜0.05）。 結論 3種儀器的中央角膜厚度測量值不可互換，LASIK術后A型超聲和Pentacam量值較為準確。Objective To compare the difference in measurements of central corneal thickness (CCT) using A-scan, OrbscanⅡand Pentacam before and after laser in situ keratomileusis (LASIK). Methods Between October 2010 and March 2011, the CCT of 137 patients (274 eyes) were measured by A-scan, OrbscanⅡ and Pentacam, and the results were analyzed by paired t-tests and Pearson correlation. Results Before LASIK, the values of CCT measured by A-scan, OrbscanⅡ and Pentacam were (526.6 ± 34.1), (516.6 ± 34.2), and (539.8 ± 31.5) μm respectively; paired t-tests showed the CCT values obtained with Pentacam were significantly higher than those with other methods (P＜0.05), but there were no statistical significant differences between OrbscanⅡand Pentacam measurements (P＞0.05). Six months after LASIK, the values of CCT measured by A-scan, OrbscanⅡand Pentacam was (448.2 ± 48.5), (391.9 ± 58.5), and (451.5 ± 46.4) μm respectively; the CCT values obtained with A-scan and Pentacam didn’t differ much from each other (P＞0.05), and the CCT values obtained with OrbscanⅡwere lower than those obtained with A-scan and Pentacam. There was a high correlation between A-scan and Pentacam measurements. Conclusion The these methods measuring CCT could not be used interchangeably, and A-scan and Pentacam after LASIK were more precise than OrbscanⅡ.
