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        west china medical publishers
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        find Keyword "采集" 14 results
        • Report of An Early Case of Multiple Myeloma Treated by Bortezomib and the Literature Review

          目的:探討蛋白酶體抑制劑——硼替佐米對初治多發性骨髓瘤的療效及對移植造血干細胞采集的影響。方法:對一例初發的中年男性多發性骨髓瘤患者使用硼替佐米+地塞米松+反應停(VTD)的方案進行化療,獲得緩解后采集外周血造血干細胞。結果:應用以硼替佐米為基礎的方案治療3個療程后,患者即獲得完全緩解;完成4個療程化療后成功采集足夠數量的外周血造血干細胞;完成6個療程化療后,進入維持治療,至今已完全緩解17個月。治療過程中除惡心、嘔吐外無其他明顯不良反應。結論:硼替佐米用于初治多發性骨髓瘤有良好的治療效果,不良反應少,不影響造血干細胞采集。

          Release date:2016-09-08 10:14 Export PDF Favorites Scan
        • Development and Design of Portable Sleep Electroencephalogram Monitoring System

          The growing rate of public health problem for increasing number of people afflicted with poor sleep quality suggests the importance of developing portable sleep electroencephalogram (EEG) monitoring systems. The system could record the overnight EEG signal, classify sleep stages automatically, and grade the sleep quality. We in our laboratory collected the signals in an easy way using a single channel with three electrodes which were placed in frontal position in case of the electrode drop-off during sleep. For a test, either silver disc electrodes or disposable medical electrocardiographic electrodes were used. Sleep EEG recorded by the two types of electrodes was compared to each other so as to find out which type was more suitable. Two algorithms were used for sleep EEG processing, i.e. amplitude-integrated EEG (aEEG) algorithm and sample entropy algorithm. Results showed that both algorithms could perform sleep stage classification and quality evaluation automatically. The present designed system could be used to monitor overnight sleep and provide quantitative evaluation.

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        • Advances in digital twins technology of human skeletal muscle

          The human skeletal muscle drives skeletal movement through contraction. Embedding its functional information into the human morphological framework and constructing a digital twin of skeletal muscle for simulating physical and physiological functions of skeletal muscle are of great significance for the study of "virtual physiological humans". Based on relevant literature both domestically and internationally, this paper firstly summarizes the technical framework for constructing skeletal muscle digital twins, and then provides a review from five aspects including skeletal muscle digital twins modeling technology, skeletal muscle data collection technology, simulation analysis technology, simulation platform and human medical image database. On this basis, it is pointed out that further research is needed in areas such as skeletal muscle model generalization, accuracy improvement, and model coupling. The methods and means of constructing skeletal muscle digital twins summarized in the paper are expected to provide reference for researchers in this field, and the development direction pointed out can serve as the next focus of research.

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        • Research and application implementation of the Internet of Things scheme for intensive care unit medical equipment

          The intensive care unit (ICU) is a highly equipment-intensive area with a wide variety of medical devices, and the accuracy and timeliness of medical equipment data collection are highly demanded. The integration of the Internet of Things (IoT) into ICU medical devices is of great significance for enhancing the quality of medical care and nursing, as well as for the advancement of digital and intelligent ICUs. This study focuses on the construction of the IOT for ICU medical devices and proposes innovative solutions, including the overall architecture design, devices connection, data collection, data standardization, platform construction and application implementation. The overall architecture was designed according to the perception layer, network layer, platform layer and application layer; three modes of device connection and data acquisition were proposed; data standardization based on Integrating the Healthcare Enterprise-Patient Care Device (IHE-PCD) was proposed. This study was practically verified in the Chinese People’s Liberation Army General Hospital, a total of 122 devices in four ICU wards were connected to the IoT, storing 21.76 billion data items, with a data volume of 12.5 TB, which solved the problem of difficult systematic medical equipment data collection and data integration in ICUs. The remarkable results achieved proved the feasibility and reliability of this study. The research results of this paper provide a solution reference for the construction of hospital ICU IoT, offer more abundant data for medical big data analysis research, which can support the improvement of ICU medical services and promote the development of ICU to digitalization and intelligence.

          Release date:2025-02-21 03:20 Export PDF Favorites Scan
        • A gait signal acquisition and parameter characterization method based on foot pressure detection combined with Azure Kinect system

          The gait acquisition system can be used for gait analysis. The traditional wearable gait acquisition system will lead to large errors in gait parameters due to different wearing positions of sensors. The gait acquisition system based on marker method is expensive and needs to be used by combining with the force measurement system under the guidance of rehabilitation doctors. Due to the complex operation, it is inconvenient for clinical application. In this paper, a gait signal acquisition system that combines foot pressure detection and Azure Kinect system is designed. Fifteen subjects are organized to participate in gait test, and relevant data are collected. The calculation method of gait spatiotemporal parameters and joint angle parameters is proposed, and the consistency analysis and error analysis of the gait parameters of proposed system and camera marking method are carried out. The results show that the parameters obtained by the two systems have good consistency (Pearson correlation coefficient r ≥ 0.9, P < 0.05) and have small error (root mean square error of gait parameters is less than 0.1, root mean square error of joint angle parameters is less than 6). In conclusion, the gait acquisition system and its parameter extraction method proposed in this paper can provide reliable data acquisition results as a theoretical basis for gait feature analysis in clinical medicine.

          Release date:2023-06-25 02:49 Export PDF Favorites Scan
        • ASSEMBLING AND CLINICAL APPLICATION OF VIDEO OUTPUT SYSTEM UTILIZING TEACHING SIGHT GLASS OF SURGICAL MICROSCOPE

          Objective To investigate the assembl ing and cl inical appl ication of the video output system util izing teaching sight glass of surgical microscope. Methods Between June 2009 and April 2010, 10 patients with craniocervical junction malformation were treated by the method of transoral-transpharyngeal approach with the microscope and videooutput system under the direct vision. There were 6 males and 4 females with an average age of 32 years (range, 13-52 years). Three cases had the history of injury and 7 cases had no history of definite injury. The disease duration was from 10 months to 12 years (median, 5 years). The main cl inical symptoms were brevicoll is or torticoll is; 2 patients had malformation appearance and 4 patients had occi put-cervical pain. The physical examination showed that all patients had the symptoms that upper cervical cord was damaged; the imaging examination showed that all patients had basilar invagination, atlantoaxial dislocation, and ossification. Before and after operations, the functions of nerve were evaluated by Japanese Orthopaedic Association (JOA) scoring, the improvement rate was calculated to evaluate the efficacy. Results By the video output system assembly, 15.1 mill ion pixels high-definition images could be collected and reached 1 920 × 1 080 pixels video camera, so assistants or medical students could watch the cl inical operation directly. All patients had no neural injury or cerebrospinal fluid leakage during operation. Basilar invagination and atlantoaxial dislocation were corrected. Infection at incision occurred in 1 patient; other incisions healed by first intention without early compl ication. All patients were followed up 6-16 months (mean, 13.5 months). The average JOA score was increased from 10.2 preoperatively to 15.5 at 6 months postoperatively with an improvement rate of 77.9%. At 12 months after operation, bony fusions were achieved. Conclusion The miscroscope and video output system can improve the effectiveness of the original surgical microscope. It makes visual fields much clearer and operations more accuratewith a few compl ications.

          Release date:2016-08-31 05:42 Export PDF Favorites Scan
        • 靜脈留置針在血藥濃度監測中的應用

          目的 探討靜脈留置針在血藥濃度監測中的應用。 方法 2011年3月-8月,對14例行口服嗎替麥考酚酯治療的天皰瘡患者,其服藥前、首次服藥后30 min,1、2、4、6、8、12 h的血藥濃度,采用靜脈留置針進行血標本的采集與監測。 結果 按服藥前后各時間點抽樣要求,順利完成對14例患者共112次血樣采集。 結論 在對患者進行血藥濃度監測時,可采用靜脈留置針行血標本的采集,以減輕患者的痛苦。

          Release date:2016-09-08 09:17 Export PDF Favorites Scan
        • Application of standardized patients in the teaching of internal medical practice for international students

          Objective To explore the application value of standardized patient (SP)-based teaching method in the teaching of medical history taking for international students. Methods During the autumn semester of 2017, 96 international medical students were randomly divided into two groups, with 48 students in the SP-based teaching group and 48 students in the conventional teaching group. The test scores of medical history taking in English in internal medical practice of the two groups were compared. The teaching feedback from the international students was collected and evaluated by online questionnaire survey. Results The scores of medical history taking examination in internal medical practice of the students using SP-based teaching method were higher than those of the students using conventional teaching method (86.5±9.7 vs.78.2±10.6), and the difference was statistically significant (t=3.983, P<0.001). According to the questionnaire analysis, in terms of whether the current teaching method could enhance learning interest, improve communication ability, promote clinical skills, train clinical thinking, and highlight humanistic care, students with positive views in the SP-based teaching group accounted for 92.86%, 97.62%, 85.71%, 90.48%, and 95.24%, respectively, while students with positive views in the conventional teaching group accounted for 90.00%, 87.50%, 82.50%, 77.50%, and 97.50%, respectively, and the differences were not statistically significant (P>0.05). Conclusions Well-trained SP has a good application value in clinical practice of internal medicine and diagnostics teaching for international students. SP-based teaching method has been accepted and supported by the majority of international medical students who have experienced it.

          Release date:2019-01-23 01:20 Export PDF Favorites Scan
        • 成分治療機行自體造血干細胞采集中的持續靜脈補鈣方法及護理

          目的總結成分治療機行自體造血干細胞采集中采用持續靜脈補鈣方法預防低鈣血癥的護理方法。 方法選取2012年11月-2014年2月進行自體造血干細胞采集患者,在采集干細胞過程中為預防低鈣血癥進行預防性補鈣,即采集30 min后予10%葡萄糖酸鈣注射液30 mL+5%葡萄糖溶液250 mL同期緩慢靜脈滴入,60 mL/h,觀察采集過程中患者的枸櫞酸鈉中毒反應以及采集過程順利與否。 結果30例患者共采集44次,41次無不良反應,3次出現不同程度口唇麻木者將補鈣速度調至100 mL/h,30 min后不良反應消失。 結論采用適當的補鈣時機和方法在自體造血干細胞采集時能有效預防低鈣血癥的發生,其成本低,作用時間較長,操作簡便,安全性高,很大程度上減輕患者的痛苦,讓采集過程更加順利。

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        • Research on Visualization of Ultrasonic Rhinitis Therapeutic Apparatus Based on V4L2

          This paper reports the study and design of a visualization system of the ultrasonic rhinitis therapeutic apparatus with the function of endoscopic sinus. On Linux operating platform, we captured the video data of a video capture card that connected the endoscopic sinus using Video4Linux (V4L2) that was provided by the operating system. The video images were displayed by Qt. The visualization system solved the problem that the current ultrasonic rhinitis therapeutic apparatus had to rely on the large and expensive endoscopy equipment. And this simplified the doctors' operation, met the need of monitoring nasal cavity in the process of operating, greatly reduced the costs of treatment and would contribute to the promotion of the instrument. As a result, it has been tested that the nasal endoscopic image achieved by the system is clear and smooth, and fully meet the clinical needs of ultrasonic treatment of rhinitis.

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