Objective
To study the expression of the fibronectin (FN) and beta;1 integrin (beta;1) in epiretinal membranes(ERM) of eyes with proliferative vitreoretinopathy(PVR).
Methods
wenty epiretinal membranes were obtained from eyes undergone vitrectomy for retinal detachment complicated with PVR and observed by immunohistochemical methods.
Results
Overexpression of FN and beta;1 were observed in 18 and 16 membranes respectively．
Conclusion
The synergism of FN and beta;1 in their action mignt be one of the important roles in the development of PVR.
(Chin J Ocul Fundus Dis, 2001,17:119-121)
