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        west china medical publishers
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        find Author "CHEN Guoping" 3 results
        • Clinical Study on Joint Use of Neuroprotectant and Early Intervention in the Neonates with Severe Hyperbilirubinemia

          目的:觀察神經保護劑及早期干預聯合應用對重癥新生兒高膽紅素血癥神經行為預后的影響。方法:將2007年1月至2008年6月收治重癥新生兒高膽紅素血癥患兒67例隨機分為常規治療組和綜合治療組2組。 常規治療組按照新生兒黃疸干預推薦方案,給與對癥治療;藥物治療;藍光治療;周圍血管法同步換血等常規治療。綜合治療組在常規治療基礎上,同時給與新生兒撫觸1天2次和神經保護劑神經節苷脂20mg/d×10天,并在經搶救治療進入恢復期后,按照《0~3 歲早期干預大綱》采用醫院和家庭相結合的方式從視,聽,觸,運動等各方面給予早期干預至6月齡。兩組患兒均在6月齡采用北京-Gesell嬰幼兒發育診斷量表進行智能測試,比較各組發育商(DQ)。同時對兩組后遺癥發生機率比較。結果:患兒6月齡時,綜合治療組與常規治療組在大運動,語言,個人 社交及適應性4個能區均有顯著差異(Plt;0.01),精細動作能區有明顯差異(Plt;0.05),差別有統計學意義。綜合治療組與常規治療組后遺癥發生率比較(Plt;0.05),差異有統計學意義。結論:急性期神經保護劑及早期干預聯合應用可促進重癥新生兒高膽紅素血癥患兒的智能發育,減少神經行為后遺癥的發生。

          Release date:2016-09-08 10:02 Export PDF Favorites Scan
        • Construction of finite element model of left atrial diverticulum based on computed tomography and reverse engineering softwares

          This paper aims to explore the feasibility of building a finite element model of left atrial diverticulum (LAD) using reverse engineering software based on computed tomography (CT) images. The study was based on a three-dimensional cardiac CT images of a atrial fibrillation patient with LAD. The left atrium and LAD anatomical features were accurately reproduced by using Geomagic Studio 12 and Mimics 15 reverse engineering software. In addition, one left atrial model with LAD and one without LAD were created with ANSYS finite element analysis software, and the validity of the two models were verified. The results show that it is feasible to establish the LAD finite element model based on cardiac three-dimensional CT images using reverse engineering software. The results of this paper will lay a theoretical foundation for further hemodynamic analysis of LAD.

          Release date:2019-02-18 02:31 Export PDF Favorites Scan
        • Treatment of giant cell tumor of bone around knee joint with three-dimensional printing personalized prosthesis

          ObjectiveTo investigate the short-term effectiveness of three-dimensional (3D) printing personalized prosthesis in the treatment of giant cell tumor of bone around knee joint.MethodsA clinical data of 9 patients with giant cell tumor of bone around knee joints and met the inclusive criteria between May 2014 and August 2017 was retrospectively analysed. There were 4 males and 5 females, with an average age of 35.8 years (range, 24-50 years). The lesion located at the distal femur in 4 cases and at the proximal tibia in 5 cases. The disease duration was 5-25 months (mean, 12.9 months). According to Campanacci grading, there were 2 patients of grade Ⅰ and 7 of grade Ⅱ. The 3D printing personalized prosthesis was designed based on the CT scanning and 3D reconstruction prepared before operation. All patients were treated with the tumor resection and 3D printing personalized prosthesis reconstruction. The radiological examination was taken to observe the tumor recurrence and the Musculoskeletal Tumor Society 1993 (MSTS93) score was used to evaluate the knee function.ResultsAll operations were successful and all incisions healed by first intention without early complications. All patients were followed up 24-40 months (mean, 31.2 months). At last follow-up, no complication such as pain, pathological fracture, prosthesis loosening, or tumor recurrence occurred. The MSTS93 score was 20-29 (mean, 24.7). The knee function was rated as excellent in 6 cases and good in 3 cases, with the excellent and good rate of 100%. ConclusionFor giant cell tumor of bone around knee joint, 3D printing personalized prosthesis has the advantages of bio-fusion with host bone, mechanical stability, good joint function, and ideal short-term effectiveness. But the middle- and long-term effectiveness still need to be further observed.

          Release date:2020-07-07 07:58 Export PDF Favorites Scan
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