【摘要】 目的 對住院的手足口病患兒，在相同治療和護理基礎上，應用復方黃連素片劑融入復方爐甘石洗劑外用觀察其療效和安全性，為傳染病的防制提供臨床經驗。 方法 2008年5月-2010年5月收治手足口病患兒184例，采用隨機分組法，以復方黃連素片劑融入復方爐甘石洗劑外用92例為治療組，未用復方黃連素片劑融入復方爐甘石洗劑外用92例為對照組，進行療效比較。 結果 治療組5 d痊愈率為94%，總有效率為100%，與對照組比較差異有統計學意義（Plt;0.01）。 結論 應用復方黃連素片劑融入復方爐甘石洗劑外用治療手足口病安全可靠。【Abstract】 Objective To observe the therapeutic and nursing effect on hand-foot-mouth disease (HFMD) with infection after medication for external use. Methods A total of 184 patients with HFMD from May 2008 to May 2010 were randomly divided into two groups: 92 patients in the treatment group underwent medication for the external use topical with berberine tablet blending in calamine lotion for, and another 92 patients in the control group didn’t undergone the medication for the external use. Results The total cure rate within 5 days in treatment group was 94% and the total effective rate was 100%, which was significantly different from that in the control group (Plt;0.01). Conclusion Berberine tablet blending in calamine lotion application is safe and effective on patients with HFMD with infection.
Stroke is characterized by high morbidity, mortality, disability, recurrence rate and economic burden. In addition to secondary prevention after stroke, rehabilitation is one of the most important means for the recovery of post-stroke dysfunction. Traditional rehabilitation methods have limited effect on the recovery of function for patients after stroke. Mirror therapy is a safe and feasible treatment, which is widely used as a rehabilitation method of many diseases. This paper reviews literatures on the application of mirror therapy in stroke rehabilitation (limb dysfunction, unilateral neglect, swallowing disorder and complex regional pain syndrome) at home and abroad, and summarizes it’s potential mechanisms, so as to provide references to future research and application of mirror therapy.
Objective To investigate the differences in postoperative mortality and identify potential influential factors in patients with a systemic left ventricle (SLV) versus a systemic right ventricle (SRV) following total cavopulmonary connection (TCPC). MethodsWe retrospectively collected data from functional single ventricle patients who underwent TCPC at the Department of Cardiac Surgery, Guangdong Provincial People’s Hospital, between October 2004 and July 2021. The cohort was categorized based on ventricular morphology into two groups: a SLV group and a SRV group. All procedures were performed via a median sternotomy under cardiopulmonary bypass. ResultsA total of 195 patients were included, comprising 108 patients in the SLV group (69 males, 39 females) and 87 in the SRV group (61 males, 26 females). The median age at surgery was 5.7 (IQR, 4.0-11.2) years, and the median body mass index (BMI) was 15.1 (IQR, 13.5-16.2) kg/m2 for the SLV group. For the SRV group, the median age was 5.7 (IQR, 4.1-8.9) years, and the median BMI was 14.7 (IQR, 13.6-15.9) kg/m2. The proportion of patients with situs inversus, heterotaxy syndrome, and moderate or greater atrioventricular valve regurgitation was significantly higher in the SRV group. Patients in the SRV group had a higher rate of fenestration and experienced longer aortic cross-clamp, cardiopulmonary bypass, and operative times, as well as prolonged postoperative hospital stays and chest tube durations. However, there were no statistical differences in early or late mortality between the two groups (P>0.05). Multivariate analysis identified pulmonary vascular resistance, postoperative aspartate aminotransferase, and postoperative creatinine as independent risk factors for mortality, while postoperative percutaneous oxygen saturation and hemoglobin levels were identified as protective factors. Conclusion The post-TCPC survival rate in patients with a SRV is non-inferior to that in patients with a SLV. However, the overall long-term mortality for both groups remains high, warranting close monitoring of the long-term survival outcomes in this patient population.
