ObjectiveTo understand the current status of oral frailty in older patients with colostomy, and analyze the factors affecting oral frailty. MethodsA retrospective analysis was conducted on older patients with colostomy who visited the Department of Gastrointestinal Surgery, Shandong Provincial Hospital from May 2023 to December 2023. The questionnaire survey was conducted using the general data questionnaire, oral frailty index-8 (OFI-8), the edmonton frail scale (EFS), and the nutritional risk screening score 2002. According to the OFI-8 score, the patients were divided into oral frailty group and non-oral frailty group, and the two-classified logistic regression model was used for multivariate analysis to explore the factors affecting the oral frailty of older patients. ResultsA total of 283 survey subjects were collected, and the incidence of oral frailty in older patients was 66.4% (188/283). Multivariate analysis showed that old age [OR=1.181, 95% CI (1.015, 1.373), P=0.032], history of smoking [OR=2.721, 95%CI (1.122, 6.599), P=0.027], history of alcohol [OR=2.878, 95%CI (1.185, 6.991), P=0.020], dentures [OR=3.173, 95%CI (1.297, 7.759), P=0.011], postoperative oral diseases≥2 [OR=5.802, 95%CI (1.911, 17.615), P=0.002], nutritional risk [OR=2.744, 95%CI (1.033, 7.284), P=0.043], high EFS score [OR=1.823, 95% CI (1.309, 2.538), P<0.001], permanent stoma [OR=2.659, 95%CI (1.126, 6.275), P=0.026] were risk factors for oral frailty in older patients with colostomy. ConclusionsThe incidence of oral frailty in older patients with colostomy is relatively high. We should pay more attention to the patients’ oral frailty, and implement precise intervention measures for high-risk factors to prevent the occurrence of oral frailty or improve the condition of oral frailty.