Congenital toxoplasmosis is one of the most common types of intrauterine infection, with the triad of retinal choroiditis, intracranial calcification, and hydrocephalus as the main clinical manifestations, which can lead to serious sequelae such as cerebral palsy, cognitive impairment and visual impairment. Therefore, early diagnosis and early treatment are important to improve the prognosis of patients. Recommended treatment options include pyrimethamine, sulfadiazine combined with folic acid, or new drugs such as azithromycin and atorvastatin. This article reviews the research progress of epidemiology, clinical manifestations, diagnosis and treatment of congenital toxoplasmosis, in order to provide a reference for clinicians to improve their understanding of clinical diagnosis and treatment of this disease.
