Objective To analyze the research progress and current situation in the field of chemotherapy-induced premature ovarian failure by bibliometrics, so as to provide scientific and efficient research path for researchers. Methods All the literature on chemotherapy-induced premature ovarian failure from 2015 to 2024 was retrieved from the Web of Science Core Collection. CiteSpace and VOSviewer software were used to conduct bibliometric analyses of authors, institutions, keywords, co-cited documents, etc., and to draw the relational graphs. Results A total of 567 papers were included. The annual research output increased slightly, and the number of papers published by Chinese researchers ranked first. The 49 selected keywords were divided into 11 clusters, and the emerging keywords showed that the research hotspots in recent years focused on more in-depth mechanism studies, such as primary ovarian insufficiency and fertility preservation in premenopausal patients, which might continue to be research hotspots. Conclusions In recent years, the research heat of chemotherapy-induced premature ovarian failure has been increasing, and Chinese scholars have made outstanding contributions, however, it is necessary to further strengthen the scientific research cooperation among researchers. Fertility preservation, hormone replacement therapy, in vitro transplantation may become the hotspots of future research, and the depth and refinement of research should be further promoted on the basis of multi-center and multi-disciplinary cross.
