【
Abstract
】
Objective
To explore the effect of gamma-globulin in evaluating hepatic functional reservation in patients with liver tumor. Methods Serum protein electrophoresis (SPE) was performed on 30 patients with liver tumor to get gamma-globulin and preoperative Child-Pugh classification. Then the relations between gamma-globulin and preoperative and postoperative Child-Pugh classification were studied. While with gamma-globulin as evaluating standard, the validity compared with Child-Pugh classification were studied. Results The gamma-globulin was lower in classification A patients
〔（
21.053 3
±
6.001 4)%
〕
than that in classification B
〔
(28.800 0
±
8.672 5)%
〕
before operation. While the gamma-globulin
〔
(21.022 0
±
5.354 6)%
〕
of classification A patients after operation was also lower than that of classification B/C
〔
(29.556 0
±
7.698 5)%
〕
. These differences were significant (P
＜
0.05). With gamma-globulin gt;30% as evaluating standard
，
the sensitivity and specificity were 80.00% and 96.00%, respectively. Conclusion Gamma-globulin can reflect hepatic functional reservation in patients with liver tumor. Combining gamma-globulin and Child-Pugh classification can evaluate hepatic functional reservation more objectively.
