Objective To evaluate the therapeutic effects of D1 and D2 operative methods for advanced gastric carcinoma. Methods 60 cases of the resectably distal gastric cancer were colleted prospectively and they were randomly divided into group D1 (30 cases) and group D2 (30 cases). They were operated respectively by the doctors with equivalent grade in two groups.Results No patients in the two groups died from the operation. The rate of recurrence and metastasis in group D1 and D2 was 40.0% and 3.3% (P＜0.01) respectively in a year, 53.3% and 10.0%(P＜0.01) in two years, 56.6% and 13.3% (P＜0.01) in three years, 60.0% and 16.7% (P＜0.01) in four years； The survival rates in group D1 and D2 were 73.3% and 96.7%(P＜0.05) in a year, 59.3% and 96.5% (P＜0.01) in two years, 53.6% and 83.3% (P＜0.05) in three years, 44.4% and 80.0% (P＞0.05) in four years, respectively. ConclusionIn reducing the recurrent rate of gastric cancer and increasing the postopertive survival rate, the D2 operative method is much better than the D1 operative method, and it can be the first choice for advanced gastric carcinoma.
