ObjectiveTo systematically review the association between H type hypertension and acute coronary syndromes in China.
MethodsWe electronically searched databases including PubMed, Web of Science, CNKI, CBM, VIP and WanFang Data databases to collect case-control studies about the association between H type hypertension and acute coronary syndromes among the Chinese population from inception to May, 2015. Two reviewers independently screened literature, extracted data, and evaluated the risk of bias of included studies. Then, meta-analysis was performed by using RevMan 5.2 software.
ResultsA total 6 studies involving 992 patients were included. Among these cases, 438 cases were in the acute coronary syndromes group (case group) and 554 were in the control group. The results of metaanalysis showed that: proportion of H type hypertension patients in the case group was significantly higher than that in the control group (OR=3.32, 95%CI 2.21 to 4.98, P<0.000 01).
ConclusionCurrent evidence shows that, H type hypertension may be associated with acute coronary syndromes in the Chinese population. Due to the limited quantity and quality of included studies, more high quality studies are needed to verify the above conclusion.
