Sepsis 已經成為危重癥醫學中較為常見的一種綜合征，它定義為因病原體感染而引起的全身性炎癥反應綜合征。嚴重Sepsis患者預后不佳，治療上也較為困難，特別是合并Septic Shock和多器官功能不全綜合征（MODS）的患者，死亡率仍然較高，因此近年來在臨床及研究上均已引起明顯的重視。為了能促進Sepsis的研究及治療，國際上多個醫學專科分會聯合發起“拯救Sepsis運動（Surviving Sepsis Campaign, SSC）”，并于2004年首次發表了相應的指南，即Surviving Sepsis Campaign Guideline for Management of Severe Sepsis and Septic Shock。今年初SSC再次發表了新版的指南，主要是結合近年的研究成果而在原版的基礎上進行適當的補充和更新，以指導臨床上嚴重Sepsis的搶救及治療。
ObjectiveTo understand the relationship between post-traumatic stress disorder (PSTD) and perceived stress in suspected coronavirus disease 2019 (COVID-19) patients quarantined in hospital.MethodsA cross-sectional study of 93 suspected COVID-19 patients in one of grade-A tertiary hospital in Southwest China was carried out to evaluate the incidence of perceived stress and post-traumatic stress symptoms among these patients using the standardized Perceived Stress Scale-10 (PSS-10) and PTSD Checklist-5 (PCL-5), respectively. Pearson correlation was used to analyze the correlation between PCL-5 and PSS-10 scores.ResultsTotal PSS-10 and PCL-5 scores were 16.7±5.2 and 17.0±11.6 in 93 suspected COVID-19 patients, respectively. Positive correlations between PSS-10 and PCL-5 scores were detected (Pearson’s r=0.722, P=0.000).ConclusionsThe occurrence and development of PSTD of suspected COVID-19 patients have the relationship with the early perceived pressure. It suggests that medical staff should identify and intervene the perceived pressure level of patients who are under quarantine as suspected COVID-19 early and effectively, so as to reduce the occurrence of PTSD.
