Objective
To detect the clinical manifestations, diagnos is and treatment of painful
ophthalmoplegia syndrome.
Methods
The data of onset, clinical m anifestations, laboratory examination, imaging and
treatment from 12 patients with painful ophthalmoplegia, hospitalized from Mar,
2000 to Aug. 2005, were retro spectively analyzed.
Results
Multiple characters and extents of the headache were found in these 12 patients.
The involved cranial nerves included the Ⅲ,Ⅳ, V1-2 and Ⅵ, especially the cranial
nerve Ⅲ(83.3%). Several simultaneously in volved cranial nerves were frequently found (75%). Diseases which could cause hea dache along with ophthalmoplegia
must be excluded before the diagnosis of the painful ophthalmoplegia syndrome was established. The examination of imaging was important for the diagnosis of
painful ophthalmoplegia syndrome. Patients were sensitively responsive to
cortico-steoid therapy. The cure rate was 75%.
Conclusion
The features of clinical manifestations, imaging results and the patients response to cortico-steoid therapy accorded with the etiology of nonspecific inflammation granuloma. Cortico-steoid therapy is effective after the definitude of the disease.
(Chin J Ocul Fundus Dis, 2006,22:385-386)
Objective
To observe the clinical manifestations and treatment of ocular myasthenia gravis.
Methods
The clinical manifestations, results of laboratory examination and thymic CT, and
therapeutic data of 84 patients with ocular myasthenia gravis, hospitalized from
July, 1998 to July, 2005, were retrospective ly analyzed.
Results
These patients were 2.5 to 70 years old. All of the patients had ptosis, includine
35.77% with diplopia 25% with strabismus; 1 with obnormal sphincter muscle
and 1 with blurry vision.The positive rate of examination of AchR antibody was
27.6%, and abnormal rate of examination of thymic CT was 64.3%. The cure rate was 48.1% in oral administration with tabellae in whomdostigmini group, 66.7%
in methylprednisolonum hormone therapy group, and 51.9%in thymectomy group.
Conclusions
Ocular myasthenia gravis is mostly involved levator palpebrae superiors and
sometimes also involved other ocular muscles. Anticholinesterase medication,
methylprednisolonum hormone therapy or thymec tomy are effective.
(Chin J Ocul Fundus Dis, 2006,22:379-381)
Using radioimmunoassay (RIA) and immunohistochemical LASB technique, the level of serum estradiol (E2), testosterone (T), progesterone (P), estrogen receptors (ER) and progesterone receptors (PR) in 30 male patients with gallstones were detected. The results showed that the level of serum P, E2/T and PR was higher. This suggests that the metabolic disorder of gonadal hormones play an important role in gallstone formation.
