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        west china medical publishers
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        find Author "LAI Li" 4 results
        • Retrospective analysis of 240 surgery-related near misses

          Objective To summarize the characteristics of surgery-related near misses including events composition, cause of incident, specialty category, personnel allocation etc, and to provide experience of feedforward control for the nurses in operating room and a clinical basis of safety standards for the management of operating rooms. Method The 240 surgery-related near misses occurred between July 2014 and July 2016 were retrospectively analyzed, using frequencies and percentiles to describe the count data. Results The 240 surgery-related near misses were mainly associated with surgical stitches (91 cases, 37.9%), surgical dressings (52 cases, 21.7%) and surgical instruments (45 cases, 18.8%). The main features of the 91 cases of surgical stitching included loss of suture needles (40.7%, 37/91) and fracture events (37.4%, 34/91). Among the 52 cases of surgical dressings, the most commonly were gauze dressing events (43 cases, 82.7%), in which 19 were with unclear numbers of retained gauzes in the reoperation patient’s body, and 15 were postoperative counting anomalies. Among the 45 cases of surgical instruments, the fracture and defect were the most common (21 cases, 46.7%). Conclusion The operation nurses should focus on the prevention of suture needle loss, the surgical dressings loss and the fracture and defect of surgical instruments, etc, to reduce or avoid the surgery-related near misses.

          Release date:2017-12-25 06:02 Export PDF Favorites Scan
        • The Effect of Traditional Tibetan Tonic Prescription Basangmusuyou Pills on Proliferation Ability of Bone Marrow Cells in Mice Injured by Radiation and Chemistry

          目的 觀察藏醫滋補方“巴桑母酥油丸”對放射線-化學復合損傷小鼠骨髓不同細胞群增殖能力的影響,探討其促進放射線-化學復合損傷機體外周血象恢復的機制。 方法 采用造血祖細胞集落分析方法、流式細胞術,檢測灌胃巴桑母酥油丸后放射線-化學復合損傷小鼠骨髓細胞中早期紅系祖細胞(CFU-E)、晚期造血祖細胞(BFU-E)、粒-巨噬系祖細胞(CFU-GM)、巨核系祖細胞(CFU-Meg)集落產率、骨髓細胞增殖周期各時相細胞比例、造血干細胞抗原-1(Sca-1)免疫表型陽性細胞數變化情況。 結果 巴桑母酥油丸組骨髓細胞S+G2/M期細胞比例高于生理鹽水組(P<0.05)和自然恢復的空白組(P<0.01);CFU-E、BFU-E、CFU-GM集落產率高于生理鹽水組和空白組(P<0.05);CFU-Meg集落產率、Sca-1+細胞數在各組間差異無統計學意義(P>0.05)。 結論 巴桑母酥油丸對放射線-化學復合損傷小鼠骨髓細胞具有促進增殖的作用,這可能是其促進放射線-化學復合損傷機體外周血象恢復的途徑,但對不同階段、不同系別的造血細胞其促進作用不同。

          Release date:2016-09-07 02:38 Export PDF Favorites Scan
        • Chlorhexidine versus povidone iodine for preventing surgical site infections: a meta-analysis

          Objective To systematically review the efficacy of chlorhexidine versus povidone iodine in the prevention of wound infections after surgeries by meta-analysis. Methods All randomized controlled trials comparing these two disinfectants were searched from databases of PubMed, The Cochrane Library (Issue 3, 2016), EMbase, WanFang Data, VIP and CNKI from inception to August 2016. Two reviewers independently screened literature, extracted data and assessed the risk of bias of included studies. Then, meta-analysis was performed using RevMan 5.2 software. Results A total of 14 randomized controlled trials were included. The results of meta-analysis showed that the chlorhexidine group had significantly lower rates in any surgical site infection (RR=0.71, 95% CI 0.58 to 0.88,P=0.001) and superficial incisional infection (RR=0.66, 95% CI 0.48 to 0.91,P=0.01) when compared with povidone iodine group. However, there were no significant differences in deep incisional infection (RR=0.51, 95% CI 0.23 to 1.11,P=0.09) and organ-space infection (RR=0.97, 95% CI 0.53 to 1.76,P=0.92) between the two groups. Furthermore, subgroup analysis revealed differences in any surgical site infection and superficial incisional infection could only be found in surgeries possibly contaminated. Conclusion Chlorhexidine may be superior in decreasing the incidence of infection in probably contaminated surgery.

          Release date:2017-05-18 02:12 Export PDF Favorites Scan
        • Associations between sarcopenia and peripheral inflammatory, nutritional factors, and prognosis in patients with gastric cancer

          Objective To investigate the relevance among sarcopenia, peripheral inflammatory, and nutritional factors, as well as the impact of sarcopenia on the prognosis of gastric cancer. Methods A total of 174 patients with gastric cancer in Department of Gastrointestinal Surgery in West China Hospital of Sichuan University from July 2016 to December 2020 were retrospectively included. The skeletal muscle index (SMI) of the third lumbar vertebra level was calculated using CT images, and male patients with SMI<52.4 cm2/m2 and female patients with SMI<38.5 cm2/m2 were considered sarcopenia. The key clinicopathological features of patients were collected for prognostic analysis. ResultsAmong the 174 patients with gastric cancer, 73 patients (41.95%) were diagnosed with sarcopenia. Compared with those of non-sarcopenia, the patients who were diagnosed with sarcopenia showed a significantly elder age and lower body mass index (BMI). In addition, males demonstrated a significantly higher rate of sarcopenia. Further, patients with sarcopenia showed a significant increasing in the incidence of postoperative pulmonary infections and length of hospitalization than patients without sarcopenia. The two groups showed significant differences in type 2 diabetes, peripheral C-reaction protein (CRP), interleukin-6 (IL-6), albumin, prealbumin, and hemoglobin. Overall, the multivariate analysis and Kaplan-Meier survival curves indicated that sarcopenic patients had a significantly lower survival rate than the non-sarcopenia patients. Conclusion Sarcopenia is closely related to higher levels of inflammation, malnutrition, and poor prognosis in patients with gastric cancer. Therefore, we should diagnose sarcopenia patients as early as possible, and give nutritional support to the patients.

          Release date:2023-02-16 04:29 Export PDF Favorites Scan
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