【摘要】 目的 觀察窄譜中波紫外線聯合復方甘草酸苷治療尋常性銀屑病的療效。 方法 2007年2月—2010年11月，將收治的126例銀屑病患者隨機分為治療組和對照組，治療組72例采用注射復方甘草酸苷與窄譜中波紫外線聯合治療，對照組54例則僅采用窄譜中波紫外線治療，以銀屑病皮損面積和療效指數（PASI）評價對比兩組療效。 結果 兩組治療后PASI評分均明顯低于治療前；治療后治療組PASI評分低于對照組，且差異有統計學意義（Plt;0.05）；兩組治療有效率分別為87.5%和79.6%，治療組療效明顯優于對照組（Plt;0.05）。 結論 窄譜中波紫外線與復方甘草酸苷聯合治療尋常性銀屑病，不良反應小，治愈率高，值得臨床推廣。【Abstract】 Objective To observe the clinical efficacy of compound glycyrrhizin combined with narrow-band ultraviolet B (NB-UVB) in treating patients with psoriasis vulgaris. Methods A total of 126 patients with psoriasis vulgaris treated in our hospital from February 2007 to November 2010 were randomly divided into the treatment group and the control group. Seventy-two patients in the treatment group were treated with NB-UVB radiotherapy combined with compound glycyrrhizin, and 54 patients in the control group were treated with NB-UVB radiotherapy alone. The curative effects were evaluated in terms of the area of injury and therapeutic effect indexes. Results The PASI score after treatment for both groups was obviously lower than before, and the score of the treatment group was significantly lower than the control group after treatment. The efficacy rate was respectively 87.5% and 79.6% for the treatment group and the control group, with a significant difference (Plt;0.05). Conclusion NB-UVB combined with compound glycyrrhizin is safe and effective in treating psoriasis vulgaris, and it is worth popularizing.
Objective
To summarize the research progress of the adenocarcinoma of esophago-gastric junction (AEG) in recent years, in order to improve the further understanding of this disease.
Method
The literatures about application and research progress of AEG were researched and reviewed.
Results
Siewert classification was a widely recognized classification for AEG, according to this classification, AEG was divided into typeⅠ, Ⅱ, and Ⅲ. Gastroesophageal reflux, Barrett’ sesophagus, and the infection of Helicobacter pylori may be the important pathogenic factors. For SiewertⅠAEG, thoracic approach was preferred commonly, and for SiewertⅡand Ⅲ AEG, total gastrectomy through abdominal approach and distal partial resection of esophagus through diaphragmatic hiatus approach were recommended. Endoscopic submucosal resection, neoadjuvant therapy, targeted therapy, and multidisciplinary team were becoming more and more important in the treatment of AEG.
Conclusions
The choice of surgical method and resection range should according to the types of AEG. Comprehensive assessment and comprehensive treatment would be performed, so that effect of treatment may be improved.
