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        west china medical publishers
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        find Author "LU Weizhong" 2 results
        • Clinical Study on Glucosamine Hydrochloride and Etofenamate Gel in the Treatment of Knee Osteoarthritis

          目的 臨床觀察鹽酸氨基葡萄糖和依托芬那酯凝膠治療膝骨關節炎(KOA)的療效。 方法 2010年6月-2012年2月,將354例KOA患者隨機分為鹽酸氨基葡萄糖組(A組)、依托芬那酯凝膠組(B組)和鹽酸氨基葡萄糖+依托芬那酯凝膠組(C組)。A組為口服鹽酸氨基葡萄糖,750 mg/次,2次/d,療程6周;B組為依托芬那酯凝膠外用,2次/d,6周為1個療程;C組為在A組的基礎上同時加用B組的方法。 結果 C組在改善行走疼痛、夜間靜息痛、晨僵方面優于A、B組,A組優于B組,差異有統計學意義(P<0.05)。總有效率A組為79.65%,B組67.28%,C組89.38%,差異有統計學意義(P<0.05)。出現不良反應A組3例,B組3例,C組4例,均較輕微,無嚴重不良事件發生。 結論 鹽酸氨基葡萄糖和依托芬那酯凝膠治療KOA均安全、有效,聯合應用時,療效進一步增強。

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        • Non-operative treatments for lumbar disc herniation: an evidence-based practice guideline

          Lumbar disc herniation (LDH) is one of the most important causes of back and leg pain, which seriously affects the quality of life of patients. As the first-line treatment for LDH, non-operative treatment can relieve 80% to 90% of symptoms among the patients with LDH. This guideline followed Guidelines for the Formulation/Revision of Clinical Treatment Guidelines in China (2022 edition) and WHO handbook for guideline development (2014 edition) to set up guideline working group. This guideline identified fourteen clinical questions through the literature review and clinical experts’ consensus. We drafted the recommendations after systematically searching and evaluating the evidence; delphi method was adopted for expert consensus on the preliminary recommendations, finally, 19 recommendations were made to guide non-operative treatments for LDH. This guideline can provide guidance for the clinical practice of Chinese and western orthopedics practitioners.

          Release date:2024-01-30 11:15 Export PDF Favorites Scan
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