Ultrasonic examination is a common method in thyroid examination, and the results are mainly composed of thyroid ultrasound images and text reports. Implementation of cross modal retrieval method of images and text reports can provide great convenience for doctors and patients, but currently there is no retrieval method to correlate thyroid ultrasound images with text reports. This paper proposes a cross-modal method based on the deep learning and improved cross-modal generative adversarial network: ①the weight sharing constraints between the fully connection layers used to construct the public representation space in the original network are changed to cosine similarity constraints, so that the network can better learn the common representation of different modal data; ②the fully connection layer is added before the cross-modal discriminator to merge the full connection layer of image and text in the original network with weight sharing. Semantic regularization is realized on the basis of inheriting the advantages of the original network weight sharing. The experimental results show that the mean average precision of cross modal retrieval method for thyroid ultrasound image and text report in this paper can reach 0.508, which is significantly higher than the traditional cross-modal method, providing a new method for cross-modal retrieval of thyroid ultrasound image and text report.
【摘要】 目的 探討腎移植術后藥物（環孢素A和鈣離子拮抗劑）、口腔衛生與牙齦增生的關系。 方法 隨訪2003年1月—2010年3月間321例腎移植患者，記錄患者術后藥物使用和口腔衛生情況，觀察牙齦增生程度。結果 〖HTSS〗口腔衛生水平與牙齦增生程度之間存在統計學相關性（rs=0.344，P=0.000），口腔衛生水平越差，牙齦增生越嚴重。服用環孢素A和鈣離子拮抗劑患者（A組）牙齦增生發生率為62.15%，高于單純服用環孢素A患者（B組）23.40%，二者比較，差異有統計學意義（χ2=39.220，P=0.000）。結論 〖HTSS〗腎移植術后環孢素A和鈣離子拮抗劑聯合應用明顯增加了牙齦增生的發病率。口腔衛生水平與牙齦增生程度之間存在重要關聯，口腔衛生差是牙齦增生的危險因素。【Abstract】 Objective To investigate the correlation between drugs (cyclosporine A and calcium channel blocker), oral hygiene and gingival hyperplasia in patients after renal transplantation. Methods We continuously followed up 321 patients undergoing renal transplantation from January 2003 to July 2009 in our hospital. The levels of oral hygiene, medication and gingival hyperplasia were recorded. Results There was a close relationship between the level of oral hygiene and the degree of gingival hyperplasia (rs=0.344, P=0.000). Higher grades of gingival hyperplasia (grades Ⅱ and Ⅲ) were found exclusively in patients who did not have good oral hygiene. There was a higher tendency of developing gingival hyperplasia among patients who received cyclosporine A and calcium channel blocker than those who only received cyclosporine A (62.15% vs. 23.40%; χ2=39.220, P=0.000). Conclusion The prevalence of gingival hyperplasia is higher in renal transplant recipients taking cyclosporine A and calcium channel blockers. There is a significant relationship between the level of oral hygiene and the development of gingival hyperplasia. Poor oral hygiene is a risk factor of gingival hyperplasia.
