Purpose
To study an animal model of retinal sheets transplantation using excimer laser.
Methods
A layer of pure photoreceptors was got by the use of excimer laser.Then the photoreceptor layer was transplanted to the subretinal space of the adult RCS rats which were an animal model of inherited retinal degeneration.The globes were enucleated one month after transplantation.Sections were made for light microscopic examninations.
Results
A layer of pure and uniform photoreceptors can be got by the use of excimer laser.The transplanted photoreceptors survived well in the subretinal space.
Conclusion
Retinal sheets transplantation using excimer laser can provide us with well oriented retinal construction and more photoreceptors after transplantation. (Chin J Ocul Fundus Dis,1998,14:209-211)
