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        west china medical publishers
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        find Author "SHI Tao" 7 results
        • Expression of Cathepsin B in Bladder Transitional Cell Carcinoma Tissues and Its Significance

          目的 探討組織蛋白酶B(CB)在膀胱移行細胞癌(TCC)中的表達以及其與TCC浸潤的關系。 方法 取TCC標本40例,TCC分級Ⅰ級23例,Ⅱ~Ⅲ級17例;表淺型TCC(Tis,Ta,T1期) 25例,浸潤型TCC(T2~4期)15例。另取10例正常膀胱組織作為對照。用鏈霉素抗生物素蛋白-過氧化物酶連接法行CB免疫組織化學染色觀察并計算CB陽性細胞百分率。 結果 正常膀胱組織中基質無明顯著色;在TCC癌組織中,CB可為細胞染色,部分基質亦有染色,部分毛細血管內皮細胞及部分成纖維細胞CB表達陽性,在癌周血管內皮細胞的陽性著色CB表達增強。CB在分級和分期高的癌組織中多為彌散陽性染色。TCC分級Ⅰ級組、TCC分級Ⅱ~Ⅲ級組、TCC分期表淺型組、TCC分期浸潤型組及正常對照組的CB陽性細胞百分比分別為10.53% ± 3.76%、21.52% ± 3.58%、11.32% ±2.69%、20.57% ± 3.25%、0.11% ± 0.18%,TCC各組均高于正常對照組(P<0.01);TCC分級Ⅱ~Ⅲ級組高于TCC分級Ⅰ級組,TCC分期浸潤型組高于TCC分期表淺型組,差異均有統計學意義(P<0.01)。 結論 CB可能成為判斷TCC進展和預后的重要指標。

          Release date:2016-09-08 09:16 Export PDF Favorites Scan
        • Treatment of Upper Urinary Tract Calculi with Minimally Invasive Percutaneous Nephrolithotomy with Holmium Laser

          【摘要】 目的 探討微創經皮腎鏡下鈥激光碎石術治療上尿路結石的方法及療效。 方法 2007年9月-2010年10月在B型超聲引導下應用微創經皮腎鏡下鈥激光碎石術治療上尿路結石138例,其中腎鹿角形結石64例,單發腎盂、腎盞結石38例,雙腎結石8例,輸尿管上段結石28例,孤立腎結石2例。 結果 136例取石成功,其中95例一期取石成功(包括雙通道取石5例),41例二期取石,2例因經皮腎穿失敗改行開放手術取石。27例術后體外震波碎石治療。平均結石清除率78.9%(109/138)。平均手術時間112 min,平均住院時間10 d,腎造瘺管平均留置時間4 d,雙J管平均留置時間4周。5例因術中出血較多需輸血。11例術后1周內出血較多,其中3例需要輸血。12例出現尿外滲。7例術后出現高熱(gt;39 ℃)。隨訪: 98例伴有腎積水,時間3~6個月,平均4個月,24例積水消失,68例積水減輕,6例無改善也無加重;22例殘余結石隨訪4~9個月,平均6個月,6例結石增大,16例結石無變化;87例隨訪12個月無殘余結石,7例結石復發。 結論 微創經皮腎鏡下鈥激光碎石術治療上尿路結石創傷小,恢復快,并發癥少,療效滿意。【Abstract】 Objective To discuss the method and the curative effect of minimally invasive percataneous nephrolithotomy (mini PCNL) with holmium laser in treating upper urinary tract calculi.  Methods From September 2007 to October 2010, 138 patients with upper urinary tract calculi were treated with mini PCNL with holmium laser under the conduction by type-B ultrasonography. Of the 138 cases, 64 patients had staghorn calculi, 38 had single renal pelvis or renal calyx stones, eight had bilateral renal calculi, 28 had upper-ureteral calculi, and two had solitary kidney calculi. Results Successful stone removal was achieved in 136 cases, among which there were 95 cases of stage-one nephrolithotomy (double tracts were used in five cases) and 41 cases of sfage-two neploolithotomy. Two cases were changed to open operation due to failures of percutaneous nephrolithotory. Extracorporeal shock-wave lithotomy was used in 27 cases after operation. The average stone removal rate was 78.9% (109/138). The average operation time was 112 minutes. The average hospital stay was 10 days. The average nephrostomy tube stay was four days. The average double J tube stay was four weeks. Five patients needed blood transfusion in operations due to a large amount of blood loss. Eleven patients suffered from massive hemorrhage one week after operation and blood transfusion was performed in three patients. Urine exosmosis happened in 12 cases. And there were seven cases of high fever (gt;39 ℃) after operation. Follow-up was done for 98 patients accompanied by hydronephrosis for a time period ranged from three to six months averaging at four months. Hydronephrosis disappeared in 24 patients, alleviated in 68 cases, and did not change in six cases. Twenty-two cases of residual calculi were followed up for a period ranged from four to nine months averaging at six months. Enlarged calculi occurred in six cases and no change happened to the calculi in 16 cases. Eighty-seven patients without residual calculi were followed up for 12 months, and there were seven cases of reoccurrence. Conclusion Treatment of upper urinary tract calculi with minimally invasive percutaneous nephrolithotomy with holmium laser is a simple and safe method with little injury, quick recovery, few complications and satisfactory results.

          Release date:2016-09-08 09:25 Export PDF Favorites Scan
        • The efficacy of staged carotid artery stenting and coronary artery bypass grafting in the treatment of coronary heart disease complicated with carotid stenosis

          ObjectiveTo evaluate the efficacy of staged carotid artery stenting and coronary artery bypass grafting in the treatment of coronary heart disease complicated with carotid stenosis. MethodsThe clinical data of patients with coronary heart disease and carotid stenosis treated in Fuwai Hospital from November 2019 to September 2021 were retrospectively analyzed. All patients underwent staged carotid artery stenting and coronary artery bypass grafting. The incidence and risk factors of severe complications such as myocardial infarction, cerebral infarction and death during the perioperative period and follow-up were analyzed. ResultsA total of 58 patients were enrolled, including 47 males and 11 females with an average age of 52-77 (64.2±5.6) years. No complications occurred before coronary artery bypass grafting. There was 1 myocardial infarction, 1 cerebral infarction and 1 death after the coronary artery bypass grafting. The early complication rate was 5.2%. During the follow-up of 18.3 months, 1 cerebral infarction and 2 deaths occurred, and the overall complication rate was 10.3%. According to Kaplan-Meier survival curve analysis, patients with symptomatic carotid stenosis (log-rank, P=0.037) and placement of close-cell (log-rank, P=0.030) had a higher risk of postoperative ischemic cerebrovascular event, and patients with previous cerebral infarction had a higher risk of postoperative severe complications (log-rank, P=0.044). ConclusionStaged carotid artery stenting and coronary artery bypass grafting is safe and feasible for the treatment of coronary heart disease complicated with carotid stenosis.

          Release date:2024-06-26 01:25 Export PDF Favorites Scan
        • Connecting hepatic vein and azygos vein by an autologous pericardial conduit to complete a Fontan procedure through a unilateral thoracotomy: A case report

          We reported a case of a six-year-old boy diagnosed of single ventricle, pulmonary atresia and interrupted inferior vena cava. After modified Blalock-Taussig shunt and bidirectional Glenn procedure, he received the Fontan procedure. The Fontan procedure was done through a unilateral thoracotomy, using an autologous pericardial conduit to connect hepatic vein and azygos vein. The result of short-term follow-up was satisfactory.

          Release date:2021-09-18 02:21 Export PDF Favorites Scan
        • Treatment of supracardiac total anomalous pulmonary venous connection in a single center

          ObjectiveTo analyze the surgical results of patients with supracardiac total anomalous pulmonary venous connection (TAPVC) in a single pediatric cardiac center.MethodsA retrospective study was conducted on 98 pediatric patients with supracardiac TAPVC receiving surgical repair from 2014 to 2019 in our center. There were 64 males and 34 females with a median surgical age of 3.0 (1.5, 7.0) months and a median weight of 5.0 (4.0, 6.0) kg. Twenty-three (23.5%) patients had preoperative pulmonary vein obstruction. Ninety-two (93.9%) patients received conventional surgical repair, while six (6.1%) patients were treated with the sutureless technique. The Cox regression model was used to analyze the data.ResultsThe median follow-up time was 26.50 (5.75, 44.25) months. There were 9 (9.2%) deaths. Lower weight at the time of repair (P=0.013) and prolonged cardiopulmonary bypass time (P=0.007) were associated with mortality. Postoperative pulmonary vein obstruction was observed in 8 (8.2%) patients. Associated risk factors for postoperative pulmonary vein obstruction included lower weight at the time of repair (P=0.042) and prolonged cardiopulmonary bypass time (P=0.002).ConclusionSurgical repair of supracardiac TAPVC has achieved satisfactory results in our center. Risk factors such as lower weight at the time of repair and prolonged cardiopulmonary bypass time are associated with a poor prognosis.

          Release date:2022-01-21 01:31 Export PDF Favorites Scan
        • A modified sutureless technique treating total anomalous pulmonary venous connection

          ObjectiveTo introduce a modified sutureless technique and its surgical results in the treatment of total anomalous pulmonary venous connection (TAPVC).MethodsClinical data of 11 patients with TAPVC who underwent the modified sutureless technique treatment from 2014 to 2019 in our center were retrospectively analyzed, including 4 males and 7 females. The median surgical age was 1.4 (0.3, 27.0) months. The median weight was 4.3 (3.5, 8.5) kg.Six (54.5%) patients were of supracardiac subtype, and five (45.5%) patients were of infracardiac subtype. Five (45.5%) patients had preoperative severe pulmonary hypertension, and three (27.3%) patients had preoperative pulmonary vein obstruction. The surgical results were compared with those of 10 patients treated with conventional surgical technique.ResultsThe median follow-up was 12 (range, 1-65) months. During the follow-up, no death or postoperative pulmonary vein obstruction occurred in the modified sutureless technique group. The perioperative data and relief of re-obstruction were superior in the modified sutureless technique group, but the difference was not statistically significant (P>0.05). The postoperative survival of the the modified sutureless technique group was better than that of the traditional surgery group (P=0.049).ConclusionThe modified sutureless technique which includes partial suture and then incising, and eversion of pulmonary vein incision, is a safe and reliable method for the treatment of TAPVC with satisfactory short-term results.

          Release date:2022-05-23 10:52 Export PDF Favorites Scan
        • Correlation between preoperative coronary angiography and postoperative acute kidney injury in cardiac surgery: A retrospective study in a single center

          Objective To explore the relationship between preoperative coronary angiography and postoperative acute kidney injury (AKI) in cardiac surgery. MethodsThe clinical data of patients who underwent coronary angiography within 30 days before cardiac surgery in the First Affiliated Hospital of Xi’an Jiaotong University from January 2015 to April 2019 were retrospectively analyzed. Univariate analysis and multivariate logistic regression analyses were used to explore the relationship between the interval from preoperative coronary angiography to cardiac surgery and postoperative AKI. ResultsFinally 1 112 patients were collected, including 700 males and 412 females, with a median age of 61 (55, 66) years. The incidence of postoperative AKI was 40.8% (454/1 112), of which grade 2-3 AKI accounted for 11.9%. Multivariate analysis showed that age (OR=1.049, 95%CI 1.022-1.077, P<0.001), body mass index (OR=1.065, 95%CI 1.010-1.123, P=0.020) and time interval between preoperative coronary angiography and cardiac surgery within 24 hours (OR=1.625, 95%CI 1.116-2.364, P=0.011) were independent predictors of postoperative AKI. Patients who underwent coronary angiography within 24 hours before surgery had a 10.6% higher incidence of postoperative AKI compared to those who underwent angiography ≥24 hours before surgery (P=0.004). Patients who underwent valve surgery with or without coronary artery bypass grafting (CABG) had a higher risk of AKI than those who only underwent CABG. The in-hospital stay of patients who developed AKI was 2 days longer than those without AKI. However, undergoing coronary angiography within 24 hours before cardiac surgery did not prolong the length of ICU stay or hospital stay, nor did it increase the risk of death or renal failure after the operation. Conclusion Undergoing coronary angiography within 24 hours before cardiac surgery increases the risk of postoperative AKI.

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