Schwannoma originating in the retroperitoneal space is relatively rare. The author reported a case of retroperitoneal Schwannoma confirmed by surgery and pathology, presented the typical CT and MRI manifestations of Schwannoma——“target signs”, described the pathophysiological mechanism and image differential diagnosis of the disease, so as to strengthen readers’ understanding of the typical signs of Schwannoma and improve the correct diagnosis rate of the disease.
Objective To set up healthcare device-technology deployment assessment model and procedures through establishing the assessment parameter system between the functions of the clinical technical requirements and devices. Methods The bidirectional assessment parameter system developed by the literature review and Delphi, then combination weighting calculated by the combination weighting method, and the proposals for function deployment performed on the cluster analysis. Results The positive coefficients of twice Delphi were 75.56% and 87.50%, respectively. The effective recovery rates of the questionnaire were higher. The structure of the bidirectional assessment parameter system acquired according to the data mining and review, Delphi and integrated analysis. We calculated the weighting for the required functions and the deployed functions of the ventilator in the ICU, ER and RR. We listed the absolute importance and rank. The proposals for the function deployment of the ventilator which met different needs in fields of the critical care medicine were produced by the cluster analysis, ranking absolute importance and the calibration of weighting based on the investigation for actual function utilized rate. Conclusion It studies healthcare device-technology deployment assessment model by sequential integrated methods and sets up bidirectional assessment parameter system based on clinical technical function requirement, and the result is effective.
ObjectiveTo explore transcatheter arterial chemoembolization (TACE) influences on prognosis of patients with BCLC stage 0–A hepatocellular carcinoma (HCC).MethodsThe clinicopathologic data of BCLC stage 0–A HCC patients underwent the radical resection in the Affiliated Hospital of Southwest Medical University from January 2006 to June 2018 were retrospectively analyzed. These patients were divided into a preoperative TACE treatment group (PTT group, n=365) and a directly surgical resection group (DSR group, n=365). The Kplan-Meier method was used to compare the overall survival (OS) and disease free survival (DFS) between the two groups. The Cox proportional hazard model was used to analyze whether the preoperative TACE was an independent factor affecting the prognosis of patient with BCLC stage 0–A HCC.ResultsA total of 465 patients with BCLC stage 0–A HCC were enrolled, including 365 patients in the DSR group and 100 patients in the PTT group. The baseline data of the two groups were similar（P>0.050）. In the cohort, the 1-, 3-, 5-, 10-year OS rates and DFS rates were 95.3%, 83.5%, 74.3%, 56.8% and 88.0%, 63.8%, 51.1%, 36.4%, respectively in the DSR group, which were 92.7%, 72.9%, 52.3%, 35.3% and 78.1%, 54.2%, 40.4%, 31.2%, respectively in the PTT group. The Kplan-Meier survival analysis showed that the OS and DFS in the DSR group were significantly better than those in the PTT group (P=0.009, P=0.033). The multivariate Cox proportional hazard model analysis showed that the preoperative TACE was the independent risk factor for the poor prognosis in the patients with BCLC stage 0–A HCC [ HR=1.389, 95% CI (1.158, 2.199), P=0.021].ConclusionsFor patients with BCLC stage 0–A HCC, preoperative TACE doesn’t improve patient’s prognosis and might reduce survival rate. If there is no special reason, direct surgery should be performed.
ObjectiveTo provide a practical reference for optimizing pediatric heart transplantation protocols in China by summarizing the perioperative management and short-term outcomes of pediatric heart transplant recipients at our center. MethodsWe retrospectively analyzed the medical records of all pediatric heart transplant patients performed at the Heart Center of the Children's Hospital, Zhejiang University School of Medicine, between June 2023 and September 2025. Data on donor and recipient demographics, indications for transplantation, use of mechanical circulatory support (MCS) as a bridge to transplant, perioperative clinical parameters, postoperative complications, immunosuppressive regimens, and follow-up outcomes were collected and analyzed. ResultsA total of 12 pediatric patients were enrolled, including 5 females and 7 males, with a median age of 9.7 (7.0, 13.0) years, all diagnosed with cardiomyopathy. MCS was used as a bridge to transplant in 58.33% of patients, including extracorporeal membrane oxygenation in 41.67% and a left ventricular assist device in 16.67%. The median donor heart cold ischemic time was 355 (306, 376) minutes. The most common postoperative complications were acute kidney injury (58.3%) and infection (58.3%). One week postoperatively, the median left ventricular ejection fraction recovered to 67.2% (61.8%, 71.0%). At discharge, 10 patients were in New York Heart Association (NYHA) functional class Ⅰ and 2 patients were in class Ⅱ. Over a follow-up period of 1 to 27 months, all patients survived with good cardiac function. ConclusionOur single-center experience demonstrates satisfactory short-term survival and cardiac function recovery in pediatric heart transplantation. Key areas requiring optimization include strategies for MCS bridging, management of prolonged donor heart cold ischemic time, and individualization of immunosuppressive regimens. Future development of a multi-center registry and genomics-guided precise immunosuppression strategies holds the potential to further improve long-term outcomes.
