Objective
To explore the effect of standardized use of antibiotics on clinical indicators after thoracic surgery, such as pulmonary infection rate, incision infection rate, average length of hospital stay and total hospitalization cost.
Methods
We selected 468 patients (an observation group) who were hospitalized and received thoracic surgery from August to October 2011, 3 months after the implementation of the preventive antibiotics use protocol for thoracic surgery in West China Hospital, Sichuan University, and selected 343 patients (a control group) in the same period of the previous year (from August to October 2010). There were 326 males and 142 females with a mean age of 52.0±15.5 years in the observation group, and 251 males and 92 females with a mean age of 51.4±15.9 years in the control group. The level of antibiotic use, medication time, antibiotics cost, postoperative incision infection, incidence of pulmonary infection, postoperative hospital stay and total hospitalization cost were compared between the two groups.
Results
Compared with the control group, the time for preventive use of antibiotics was significantly shorter in the observation group (3.6±2.4 d vs. 6.1±3.1 d, P=0.020) and the total cost of antibiotic use significantly reduced (1 230.0±2 151.0 yuan vs.2 252.0±1 764.0 yuan, P<0.001). There was no significant difference between the two groups in hospitalization cost(36 345.0±13 320.0 yuanvs. 35 821.0±11 991.0 yuan, P=0.566), postoperative hospital stay (10.6±8.4 d vs. 10.7±5.3 d, P=0.390), the incidence of postoperative wound infection or postoperative pulmonary infection (1.5% vs. 2.3%, P=0.430; 19.2% vs. 22.2%, P=0.330).
Conclusion
The standardized use of antibiotics in thoracic surgery does not cause postoperative pulmonary infection and incision infection, and has no negative impact on clinical indicators. Significantly reducing the level of antibiotics use may have a positive effect on reducing medication time, in-hospital infection and the incidence of drug-resistant strains.
ObjectiveTo summarize and analyze the standardized operational procedure and preliminary clinical outcomes of a "three-dimensional integrated" respiratory training model, and to propose a safe adjunctive intervention for the perioperative management of lung nodule ablation. MethodsClinical data from patients who underwent lung nodule ablation at West China Hospital, Sichuan University from August to December 2025 were consecutively enrolled and analyzed. Results A total of 18 patients were included, comprising 10 males and 8 females, with a mean age of (62.8±11.2) years. Following the implementation of the preoperative "three-dimensional integrated" respiratory training model, the mean breath-holding time significantly increased from (22.9±7.5) s at admission to (32.6±6.9) s preoperatively (P<0.01). The volume measured on the respiratory trainer improved from a mean of(1 247.2±518.9) mL at admission to (1 550.0±546.1) mL preoperatively (P<0.01). Ablation modalities included radiofrequency ablation in 17 (94.4%) patients and cryoablation in 1 (5.6%) patient. During the ablation procedure, the mean number of needle adjustments was (1.4±0.8) times, and the mean localization time was (15.6±4.4) min. All patients successfully completed the ablation therapy, achieving a technical success rate of 100.0% with no intraoperative complications. ConclusionThe "three-dimensional integrated" respiratory training model effectively enhances patients' surgical tolerance, cooperation, and procedural precision. It offers a new, safe, and effective perioperative management strategy, especially for high-risk patients (e.g., the elderly or those with poor lung function) who may be unable to tolerate conventional surgery. This model demonstrates promising potential for widespread clinical application.
