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Diagnostic Significance of Urinary Spot Protein:Creatinine Ratio in Eclampsia

【摘要】 目的 評價尿蛋白與尿肌酐比值檢測在子癇患者中的診斷意義。 方法 回顧分析 35例子癇患者的臨床資料。患者年齡20~34歲,平均年齡(2681±639)歲;孕周22~34周,平均孕周(2902±419)周。平均血壓(15620±1235 )mm Hg(1 mm Hg=0133 kPa)。均檢測24 h尿蛋白及點時尿檢測尿蛋白與尿肌酐比值,采用線形回歸分析尿蛋白與尿肌酐比值與24 h尿蛋白結果相關性。結果 35例患者24 h尿蛋白水平(351±116) g/24 h,〖JP〗直線回歸分析顯示尿蛋白與尿肌酐比值與24 h尿蛋白水平呈正相關(R=0897,Plt;001)。結論 尿蛋白與尿肌酐比值可能是一個重要的用于子癇患者尿蛋白篩查的指標。【Abstract】 Objective To investigate the diagnostic significance of urinary spot protein:creatinine ratio in Eclampsia.Method Thirtfive pregnant patients suffering from eclampsia with average age of (2681±639) years old were enrolled in this study.All patients were examined both urinary protein over 24 hours and urinary spot protein:creatinine ratio. The correlation between urinary protein over 24 hours to urinary spot protein:creatinine ratio with linear regression were analyzed. Result The rinary protein of 35 patients over 24 hours were (351±116) g/24 h,meanwhile the urinary spot protein:creatinine ratio were (0345±017) g/mmol. With linear regression, urinary spot protein:creatinine ratio had a positive correlation with the data of urinary protein over 24 hours (R=0897,Plt;001). Conclusion The spot protein:creatinine ratio is a reasonable test for detecting proteinuria in eclampsia pregnancy.