With the post-disaster psychological crisis has aroused wide attention, psychological first aid which can relieve psychological trauma and prevent post-traumatic disorder has been valued by many countries. However, mainly domestic psychological first aid training is simply theoretical training while its popularizing rate is low, it is urgent to learn from international experience to carry out more effective psychological first aid training. In the context of combination of medicine and industry, the paper majorly embodied virtual simulation’s potential in improving psychological intervention ability, deep learning level and self-efficacy. Furthermore, the paper analyzed and illustrated theoretical basis and function module of constructing psychological first aid training platform in detail, and prospected further improvement, which laid foundations for follow-up studies.
ObjectiveTo systematically evaluate the composition spectrum of oral microbiota diversity in patients with head and neck tumors undergoing radiotherapy. MethodsComputer searches were conducted on CNKI, CBM, WanFang Data, PubMed, Embase, and Web of Science databases to collect cohort and control studies on changes in oral microbiota in patients with head and neck tumors after radiotherapy. The search period was from January 1, 2015 to June 1, 2025. Two researchers screened and evaluated literature, extracted data, and conducted meta-analysis using RevMan 5.4 software. ResultsA total of 25 studies were included, including 731 patients with head and neck tumors and 275 healthy controls. The meta-analysis results indicated that compared with the control group not exposed to radiotherapy, the detection rates of major oral opportunistic pathogens such as Candida albicans and Streptococcus mutans had significantly increased (OR=3.62, 95%CI 2.23 to 5.89, P<0.01). The Shannon index and Chao1 index for oral alpha diversity had decreased after radiotherapy (SMD=?0.78, 95%CI ?1.23 to 0.34, P<0.01; SMD=?0.64, 95%CI ?1.14 to ?0.15, P<0.001), and the differences were statistically significant. Qualitative analysis showed that after radiotherapy, the relative abundance of Firmicutes, Streptococcus, Lactobacillus, etc. in patients increased, while the relative abundance of Clostridium, Neisseria, etc. decreased. ConclusionThere are changes in the oral microbiota of patients with head and neck tumors after radiotherapy, mainly manifested as an increase in the detection rate of opportunistic pathogens, a decrease in alpha diversity, and an imbalance in the relative abundance of some bacterial phyla. This suggests that oral care should be taken seriously for radiotherapy patients.
