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        west china medical publishers
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        find Author "YUAN Jiaying" 3 results
        • Application of Discriminant Analysis in Exploring the Diagnostic Value of Different Indicators for Prostate Cancer

          目的 應用判別分析探討不同指標對前列腺癌預測診斷中的應用價值。 方法 收集2008年1月-2011年9月經直腸超聲檢查并行經直腸超聲引導下經會陰前列腺穿刺活檢術,具有前列腺特異性抗原(PSA)、超聲圖像特征的941例患者以及其中含有血流阻力指數(RI)指標的200例患者的臨床資料,采用最近距離及極大似然判別分析兩種方法分別擬合患者年齡、血清PSA、經直腸前列腺超聲聲像圖特征以及RI指標預測前列腺癌。 結果 最近距離判別分析顯示RI對前列腺癌的判別無臨床意義。聯合患者年齡、超聲檢查和血清PSA值,判別結果提示超聲、超聲+年齡、年齡+超聲+PSA三種判別的靈敏度逐漸增加。年齡+超聲+PSA聯合指標的靈敏度為88.89%,其錯判率在20.00%以內。 結論 年齡+超聲+PSA聯合指標的極大似然判別分析可提高前列腺癌的診斷預測水平,避免前列腺穿刺給患者帶來的痛苦,并給臨床醫生的臨床診斷提供參考,有較好的應用價值。

          Release date:2016-09-07 02:34 Export PDF Favorites Scan
        • Intention of having a second child among Chinese females of childbearing age based on China’s universal two-child policy: a meta-analysis

          ObjectivesTo evaluate the intention of having a second child among females of childbearing age after the implementation of China’s universal two-child policy so as to provide evidence for further studies.MethodsCNKI, VIP, WanFang Data, CSSCI, PubMed, EMbase and ScienceDirect databases were electronically searched to collect cross-sectional studies on the intention of females of childbearing age to have a second child from January 1st, 2016 to August 31st, 2019. Two reviewers independently screened literature, extracted data and assessed risk of bias of included studies. Then, meta-analysis was performed by using R software.ResultsA total of 15 studies involving 18 820 cases were included. The results of meta-analysis showed that the fertility rate for the second child of females of childbearing age was 0.42 (95%CI 0.37 to 0.47), and the result was stable. Subgroup analysis showed that the fertility rate of second child in eastern region was higher than that in western region (0.44 vs. 0.40), in rural areas was higher than that in non-rural areas (0.46 vs. 0.35), females aged 18 to 34 was higher than those aged above 35 (0.49 vs. 0.29), and non-working females was higher than that among working females (0.48 vs. 0.40). The fertility rate of the sex of the first child being female was higher than the sex of the first child was male (0.48 vs. 0.39). The fertility rate of the couple who were both the non-only child was higher than the couple who were both the only child and who was only child while the other was non-only child (0.46 vs. 0.41 vs. 0.40).ConclusionsSince the implementation of the “universal two-child policy” in China, the fertility rate of females of childbearing age with the intention of having a second child is lower, especially those females who are from the western regions and non-rural areas, aged above 35 and the sex of the first child is male and non-dual-non-couples. Due to the quantity and quality of the included studies, more high quality studies are required to verify the above conclusions in future.

          Release date:2020-12-25 01:39 Export PDF Favorites Scan
        • Logistic Discriminant Analysis in Diagnosing Prostate Cancer Based on Chained Equation

          目的 應用基于鏈式方程的填補方法處理醫學研究中的數據缺失,并以填補后完全數據構建聯合指標的logistic判別函數,判斷其在前列腺癌的預測診斷中的應用價值。 方法 采用模擬研究,針對現實數據缺失情況模擬不同填補集結果,并以此對現實數據進行填補,以完整數據構建logistic判別,進行分析預測。 結果 填補結果隨著填補次數的增加而逐漸接近真實值并趨于穩定。聯合年齡、血清前列腺特異性抗原值、血流阻力指數及經直腸前列腺超聲檢查指標的logistic判別分析結果的靈敏度為82.39%,特異度為74.86%。 結論 聯合指標分析可提高前列腺癌的診斷預測水平,以減輕患者穿刺痛苦。

          Release date:2016-09-07 02:34 Export PDF Favorites Scan
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