目的 探討彩色多普勒超聲診斷膀胱破裂的診斷價值,以提高膀胱破裂的超聲診斷水平。 方法 回顧性分析2002年1月－2011年9月術前行彩色超聲檢查診斷膀胱破裂并經手術證實的5例患者資料，下腹加壓檢查和經導尿管注水試驗檢查作為超聲判斷有無膀胱破裂的重要檢查方法。 結果 5例均為腹膜外型膀胱破裂,彩色多普勒血流顯像明確診斷4例，漏診1例，超聲檢查是診斷膀胱破裂的有效方法。 結論 彩色多普勒超聲可以作為膀胱破裂的首選檢查技術。Objective To investigate the value of color doppler flow image (CDFI) in diagnosing bladder rupture, in order to promote the ultrasound diagnosis for the disease. Methods We retrospectively analyzed the medical data of 5 patients with bladder rupture diagnosed by CDFI before operation and confirmed by surgery. Pressing the lower abdomen and injecting water through catheter were the main examination methods for CDFI in diagnosing bladder rupture. Results All the 5 cases were bladder rupture of extraperitoneal type. Four were diagnosed with CDFI, and 1 was misdiagnosed. The ultrasonic examination was an effective technology in diagnosing bladder rupture. Conclusion CDFI may be regarded as the first diagnostic technology for bladder rupture.
Objective To evaluate the diagnostic value of Em18 by enzyme-linked immunosorbent assay (ELISA) in the patients with alveolaris echinococcosis (AE). Methods We searched MEDLINE, EMBase, PubMed, The Cochrane Library, and other databases to collect the studies which evaluated the diagnostic value of Em18 in the patients with AE. QUADAS items were used to evaluate the quality of the included studies. The heterogeneity of the included studies and meta-analyses was analyzed by using RevMan 4.2.10. The Summary Recevier Operating Characteristic (SROC) curve was performed by meta-disc. Results Eight studies involving 409 patients with AE diagnosed by the gold standard, 1105 patients with other diseases, and 216 healthy people were included. Meta analyses showed that the pooled sensitivity and pooled specificity of purified Em18 in ELISA were 91.5% and 91.7%, and those of recombinant Em18 were 92.2% and 95.7%, respectively. The AUC of SROC of purified Em18 and recombinant Em18 were 0.966 6 and 0.978 9, respectively. Conclusion Purified Em18 and recombinant Em18 have high value in diagnosis of AE by ELISA.
Objective To explore the actual experience of epileptic patients in video electroencephalogram (VEEG) examination, and to provide reference basis for formulating corresponding nursing strategies and coping methods. MethodsIn this descriptive analysis study, 18 patients (11 males and 7 females, average age 37.78±18.7 years) receiving VEEG from January to April 2022 in the Second Affiliated Hospital of Guangzhou Medical University, underwent a semi-structural interview. Information obtained from the interview was analyzed using the Colaizzi 7-step method. ResultsThe actual experience of epileptic patients in video EEG examination can be summarized into two aspects: the medical experience and the need for nursing care. The medical experience includes positive and negative experience. The positive experience includes good service attitude, professional medical services, good endurance, and being hopeful. The negative experience includes a weird feeling in the head, insomnia, inconvenience in life, eye discomfort, psychological pressure, and pain. The need for nursing care includes needs for knowledge, strong needs for communicating with doctors, needs for humanistic care and female needs for female implementing the equipment. Conclusion Epileptic patients suffer from different degrees of discomfort and psychological pressure during VEEG examination. Both negative and positive experience exist. Medical staff should improve the content of nursing services according to the nursing needs of patients and provide professional VEEG examination services to patients.
Objective To investigate the comfort status of patients undergoing video electroencephalogram (VEEG) examination and explore its influencing factors. Method A total of 177 patients who underwent VEEG examination in the Second Affiliated Hospital of Guangzhou Medical University from March 2023 to February 2024 were selected as the research subjects, and their comfort status and influencing factors during the examination period were analyzed. Result The comfort level of patients undergoing VEEG examination was at a moderate to high level (68.9% and 31.1%, respectively); complete mastery of VEEG health knowledge accounted for 49.2% and 65.5% in the moderate and high comfort groups, respectively. Logistic regression analysis results showed that head discomfort and lack of knowledge of VEEG health were independent influencing factors on the comfort of VEEG examination (P<0.05). Conclusions The comfort level of patients undergoing VEEG examination is at a moderate to high level of comfort; the overall mastery of knowledge related to video electroencephalography is insufficient and still needs further improvement; medical staff should pay attention to the comfort of patients and their mastery of relevant knowledge in examinations. They should take targeted intervention measures in a timely manner based on influencing factors, improve their knowledge level and cooperation with VEEG examinations, reduce the occurrence of discomfort during examinations, and improve the overall comfort level of VEEG examinations.
Objective To evaluate the efficacy and safety of safflower yellow pigment lyophilized power amp; dripping solution in the treatment of patients with angina, by using parenteral solution of Dan-shen root extraction as control, we designed the nonferiority clinical trial phase Ⅲ. Method 784 patients with stable angina pectoris Ⅰ, Ⅱ, Ⅲ degree and occurred more than twice per week were selected. They were randomly, stratified and blindly assigned into 5 parallel groups including one control. They were treated by using safflower yellow pigment lyophilized power (SYPLP) 80 mg + 0.9% NS 250ml, intravenously guttae, daily (trial group 1); SYPLP 160 mg + 0.9% NS 250 ml, intravenously guttae, daily (trial group 2); safflower yellow pigment lyophilized dripping solution (SYPLDS) 200 ml (160 mg), intravenously guttae, daily (trial group 3); SYPLDS 100 ml (80 mg), intravenously guttae, daily (trial group 4) and parenteral solution of Dan-shen root extraction 20 ml + 0.9% NS 250 ml, intravenously guttae, daily (control group) respectively. Efficacy and safety were evaluated after 14 days of continuous treatment. Results The angina efficacy (per-protocol population, PP): The notable effective rates of trial groups 1 to 4 and control group were 53.27%，69.44%，70.09%，55.09% and 26.00% respectively, and the effective rates were 88.79%，92.59%，93.46%，89.81% and 73.00% respectively。There was significant differences between trial group 1 and 2, trial group 3 and 4. All trial groups showed significant different effect when compared with control (P＜0.05). The effect of trial group 2 was better than those of trial group 1, and trial group 3 better than trial group 4, the four trial groups better than control group. The intention-to-treat (ITT) analysis result was almost the same to PP analysis, but trial group 3 showed no significant difference to trial group 4. In trial group 2, 3 and 4, each occurred one adverse effect, while the number was 10 in control group.Conclusion SYPLP amp; SYPLDS have certain effect on angina. They are more effective than parenteral solution of Dan-shen root extraction. No toxic side effect has been found in clinic tests.
目的 評價微創椎弓根釘內固定技術治療胸腰椎爆裂骨折的中期臨床療效。 方法 2002年9月－2007年9月，采用微創椎弓根釘內固定技術治療胸腰椎爆裂骨折30例。其中男16例，女14例;年齡18～65歲，平均39.8歲。骨折節段:胸11者3例， 胸12者13例， 腰1者12例， 腰者22例。所有骨折按AO分型，均為A3型。受傷至手術時間6 h～6 d，平均45 h。分析術后影像學指標、疼痛評分及功能障礙指數。 結果 患者均獲隨訪，隨訪時間3～9年，平均5.2年。術后各時間點傷椎前緣高度及后凸Cobb角均較術前明顯恢復（P＜0.01）。術后傷椎高度隨隨訪時間延長逐漸下降，后凸Cobb角逐漸增大。取出內固定物后、術后2年、末次隨訪時動力位X線片上骨折椎體前后相對滑移距離分別為（1.9 ± 0.3）、（2.1 ± 0.2）、（2.1 ± 0.3）mm，兩兩比較差異無統計學意義（P＞0.05）。術后1、2年及末次隨訪時疼痛視覺模擬評分分別為（2.5 ± 1.2）、（2.5 ± 1.1）、（2.4 ± 1.3）分，兩兩比較差異無統計學意義（P＞0.05）。末次隨訪時Denis腰痛分級：P1級13例，P2級12例，P3級5例。功能障礙指數為（11.4 ± 3.1）分，獲優23例、良5例、可2例。 結論 單純微創椎弓根釘內固定技術治療胸腰椎爆裂骨折中期臨床效果滿意，脊柱穩定性良好。Objective To mid-term efficacy of the technique of minimally invasive pedicle screw fixation on thoracolumbar burst fracture. Methods From September 2002 to September 2007, 30 patients were treated with minimally invasive pedicle screw fixation for thoracolumbar fracture. There were 16 males and 14 females with the mean age of 39.8 years (range,18-65 years). The injured level of was T11 in 3 cases, T12 in 13 cases, L1 in 12 cases, and L2 in 2 cases. The type of thoracolumbar fractures of all the patients was A3 according to AO classification. The during from injury to operation was 6 hours to 6 days with an average of 45 hours. The index of image and pain and disability index were evaluated after operation. Results All patients were followed up for 3 to 9 years with the mean of 5.2 years. Their average sliding distance after operation for removing internal fixation was (1.9 ± 0.3), and (2.1 ± 0.2) mm 2 years after the operation and (2.1 ± 0.3) mm at the latest follow-up. There was no significant difference (P＞0.05). Their average score was (2.51 ± 1.2) 1 year after the operation, was (2.42 ± 1.1) 2 year after the operation, and was (2.36 ± 1.3) at the latest follow-up (P＞0.05). According to Denis score system to evaluate index of lumbago, there was P1 in 13 cases, P2 in 12 cases, and P3 in 5 cases. The score of Oswestry Disability Index (ODI) was 11.4 ± 3.1 at the latest follow-up. Twenty-one cases gotexcellent therapeutic result, five cases got good and two were moderate. Conclusions Minimally invasive pedicle screw fixation for the treatment of thoracolumbar burst fracture provide satisfactory clinical results. The vertebral body and adjacent vertebral body have a good stability.
【摘要】 目的 比較腸充盈超聲檢查法與常規經腹超聲檢查法在結直腸腫瘤中的診斷價值。 方法 對2008年6月-2009年6月64例經臨床病理確診的結直腸腫瘤患者分別經腹常規超聲及腸充盈超聲檢查。在腸充盈狀態下觀察病變的形態，對病變進行定位并觀察結直腸腫瘤的彩色多普勒血流信號。比較腸充盈超聲檢查法及常規經腹超聲檢查法在結直腸腫瘤的檢出、定位和顯示血流的能力的差異。 結果 常規經腹部超聲檢查發現32例結直腸腫瘤（32/64），病灶敏感性為50%； 腸充盈超聲檢查法發現病灶55例（55/64）， 病灶敏感性為85.9%。經腹常規超聲檢查的定位準確率為21.9%（7/32），腸充盈超聲檢查法對結直腸腫瘤的定位準確率為89.1%（49/55）。兩種方法比較差異有統計學的意義（Plt;0.05）。 結論 腸充盈超聲檢查法在結直腸腫瘤的病變敏感性檢出、定位準確性等方面優于經腹常規超聲檢查；而不同病理類型的結直腸腫瘤具有不同的超聲聲像圖特征。【Abstract】 Objective To compare the diagnostic value between intraluminal contrast-enhanced hydrocolon ultrasonography and conventional transabdominal ultrasonography for of colorectal neoplasms. Methods The conventional transabdominal ultrasonography and hydrocolonic ultrasonography using an intraluminal contrast agent were performed on 62 patients from June 2008 to June 2009. The morphological features and location of the lesion were observed and the blood flow signals were observed. The different diagnostic value between conventional transabdominal ultrasonography and intraluminal contrast-enhanced hydrocolon ultrasonography was compared. Results The sensitivity of the intraluminal contrast-enhanced hydrocolon ultrasonography in the depiction of the colorectal neoplasms (55/64, 85.9%) was higher than that of the conventional transabdominal ultrasonography (32/64, 50%, Plt;0.05). And the accuracy of the intraluminal contrast-enhanced hydrocolon ultrasonography in locating the colorectal neoplasms (48/55, 87.3%) was higher than that of the conventional transabdominal ultrasonography (7/32, 53.2%, Plt;0.05). Conclusion Intraluminal contrast-enhanced hydrocolon ultrasonography is more valuable for colorectal neoplasms than conventional transabdominal ultrasonography in detecting and locating colorectal neoplasms. Colorectal neoplasms with different pathological types may have different ultrasonic features.
Objective
To discuss the nursing measures for thyroid nodule patients who undergo core-needle biopsy (CNB) guided by ultrasound.
Methods
We retrospectively analyzed the experiences and main points of nursing for 1 900 thyroid nodule patients who underwent CNB guided by ultrasound between June 2010 and May 2014.
Results
All the 1 900 patients underwent CNB successfully. The nursing time was between 5 and 15 minutes, averaging (8.0±3.7) minutes. Complications included hematoma in 25 patients (1.3%) and needle syncope reaction in 30 patients (1.6%), which were cured through symptomatic treatment. No complications such as nerve injury, anesthesia accident or death occurred. No medical disputes happened due to specimen errors or loss. The success rate of specimen collection was 98.4% (1 870/1 900), and the diagnostic accuracy was 95.3% (1 812/1 900).
Conclusions
Ultrasonography-guided CNB is a safe and reliable operation with a high success rate, high diagnosis accuracy and few complications. Being familiar with the process of nursing cooperation and correct disposal and transfer of biopsy specimens are crucial for successful CNB in patients with thyroid nodules.
Childhood obesity is a global public health problem that seriously affects the normal growth and development of children. In recent years, a large number of studies have pointed out that the intestinal microbiome is closely related to childhood obesity, and the treatment strategies targeting the intestinal microbiome have a certain improvement effect on childhood obesity. This article elaborates on the establishment and development of intestinal microbiome, intestinal microbiome characteristics, the mechanisms of intestinal microbiome involvement in the occurrence and development of childhood obesity, and potential intervention strategies, so as to provide more ideas for basic and clinical research on childhood obesity.
Objective To investigate the association between the -6843G/A polymorphism of highaffinity IgE receptor βchain ( FcεRIβ) gene and asthma susceptibility in Chinese population.Methods We searched Pubmed, EMBASE, CNKI ( Chinese National Knowledge Infrastructure) , Wanfang Datebase, VIP Database up to October 1,2009. Statistical analysis was performed with the software program RevMan 4. 2. 8 and STATA 10. 0. Results A total of 9 case-control studies were included in the meta-analysis. The results indicated that the G allele carriers had a 49% increased risk of asthma in Chinese population ( GG + GA vs. AA: OR=1. 49, 95% CI 1. 01-2. 22) . In the subgroup analysis, the results indicated that the polymorphism was associated with increased risk of asthma in the adults ( GG + GA vs. AA: OR = 1. 83, 95% CI 1. 32- 2. 52) , but not in children ( GG + GA vs. AA: OR = 1. 19, 95% CI 0. 68-2. 08) . Conclusion The -6843G/A polymorphism of FcεRIβ gene is associated with increased asthma susceptibility in Chinese population.
