Objective To investigate the risk factors of multidrug-resistant organism (MDRO) infection in patients with car accident injuries in intensive care unit (ICU), providing clinical guidance for reducing MDRO infection in car accident patients. Methods The clinical data of patients with car accident injuries in Sichuan Provincial People’s Hospital between January 1st 2019 and February 28th 2023 were collected, and the relevant data were analyzed retrospectively to explore the risk factors of MDRO infection. Results A total of 141 patients with car accident injuries were collected, of whom 30 had MDRO infection. The proportions of males (P=0.012), indwelling catheters (P=0.005), mechanical ventilation (P=0.001), length of hospital stay (P<0.001), and total treatment costs (P<0.001) in the infection group were higher than those in the non-infection group. Multiple logistic regression analysis showed that male [odds ratio (OR)=3.797, 95% confidence interval (CI) (1.174, 12.275), P=0.026], mechanical ventilation [OR=4.596, 95%CI (1.538, 13.734), P=0.006], and length of hospital stay≥20 d [OR=1.014, 95%CI (1.001, 1.028), P=0.037] were independent risk factors for MDRO infection in car accident patients. Conclusions Male, mechanical ventilation, and increased length of hospital stay are independent risk factors for MDRO infection in car accident patients. For such patients, the prevention and control measures of hospital infection should be strictly implemented to reduce the risk of infection.
Objective To explore the characteristics and influencing factors of bloodstream infection in patients with acute pancreatitis (AP), understand the characteristics of infectious pathogens, and provide references for formulating prevention and control measures for bloodstream infection in patients with AP. Methods The clinical data of patients with AP admitted to Sichuan Provincial People’s Hospital between January 2019 and February 2025 were retrospectively collected. Multivariate logistic regression analysis was employed to identify the influencing factors of bloodstream infection, and the characteristics of related pathogens was analyzed. Results A total of 1510 patients with AP were included, of whom 52 were complicated with bloodstream infections, with an infection rate of 3.44%. Multivariate logistic regression analysis revealed that gender [odds ratio (OR)=2.062, 95% confidence interval (CI) (1.045, 4.070)], hyperlipidemia [OR=0.207, 95%CI (0.077, 0.554)], and central venous catheterization [OR=4.093, 95%CI (1.765, 9.493)] were influencing factors for bloodstream infections (P<0.05). Among the pathogens identified in patients with AP complicated by bloodstream infections, Gram-negative bacteria accounted for the highest proportion (48.1%), with the main bacteria being Klebsiella pneumoniae, Escherichia coli, and Acinetobacter baumannii. Conclusions Gender, hyperlipidemia, and central venous catheterization are influencing factors for AP complicated with bloodstream infection. For with AP, it is necessary to strictly evaluate the indications for central venous catheterization and implement corresponding prevention and control measures to reduce the risk of infection.
