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Efficacy of Tazarotene Cream in the Treatment of Acne Vulgaris

摘要:目的: 觀察01%他扎羅汀乳膏(樂為)治療尋常型痤瘡的臨床療效和安全性。 方法 :以輕中度痤瘡患者40例,隨機分為治療組20例,外用01%他扎羅汀乳膏每晚1次,連用4周;對照組20例,外用01%維A酸霜每晚1次,連用4周,停藥后觀察療效。 結果 : 治療組基愈8例,顯效7例,總有效率75%; 對照組基愈5例,顯效6例,總有效率55%。兩組結果經統計學處理,差異有顯著性,P lt;005。 結論 : 他扎羅汀乳膏治療尋常型痤瘡安全、有效。Abstract: Objective: To evaluate the efficacy and safety of 01% Tazarotene Cream (Tazhaluoting Rugao)in the treatment of acne vulgaris. Methods : 40 patients, diagnosed clinically to have mild to moderate acne vulgaris were randomly and averagely assigned to two groups. 01% Tazarotene Cream and 01%Tretinoin Cream were used respectively daily night for 4 weeks on these two groups. Observe the efficacy after the ointment withdrawal. Results : 8 patients were basically cured and 7 improved in the experiment group, the total effective rate was 750%. 5 patients were basically cured and 6 improved in the control group, the total effective rate was 550%. There is significant difference between these two groups statistically (P lt;005). Conclusion : Tazarotene Cream is quite effective and safe in the treatment of acne vulgaris.