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Analysis of Bionomics and Antimicrobial Susceptibility in 102 Staphylococcus Aureus

摘要:目的: 金黃色葡萄球菌(金葡菌)的感染近年來已成為醫院內的主要致病菌,而其耐藥性也呈逐漸升高的趨勢,為了解該菌在我院的感染和耐藥情況,為臨床合理使用抗生素提供科學依據。 方法 : 用經典生理生化鑒定方法,對各種臨床標本主要來源于痰液和各種傷口膿液標本分離到的102株金葡菌進行生物學特性及藥敏試驗。 結果 : 從我們醫院2007年5月至2009年8月所分離出來的102株金葡菌中青霉素耐藥性8923%,氨芐青霉素耐藥率為9385%,沒有發現萬古霉素耐藥菌。 結論 : 除萬古霉素外,耐藥率較低的依次是利福平、苯唑青霉素、環丙沙星、呋喃妥因、阿米卡星、磺胺甲基異惡唑、紅霉素,而青霉素G、氨芐青霉素、四環素耐藥性情況非常嚴重,并且多重耐藥,耐藥性強,應引起臨床的高度重視。Abstract: Objective: To analyze the bionomics and antimicrobial susceptibility of staphylococcus aureus, which was the main pathogenic bacterium with high drug tolerance in our hospital, in order to provide the rational use of antibiotics. Methods : Samples of one hundred and two staphylococcus aureus cases from sputamentum and pus were evaluated by classic physiology and biochemistry methods to test the bionomics and antimicrobial susceptibility. Results : The drug resistance rate to penicillin, penbritin and vancomycin was 8923%, 9385% and 0, separately. Conclusion : Besides vancomycin, the drug resistance rate of rifampicin, oxazocilline, ciprofloxacin, furadantin, amikacin, sulfamethoxazole and sulfamethoxazole increased one by one. The resistance to penicillin G, penbritin and tetracycline was serious, including multidrug resistant, which should be paid highly attention.