Objective To explore the relationship between grip strength and knee joint pain in middle-aged and elderly population. Method The research data in middle-aged and elderlypopulation was obtained from the CHARLS database between 2011and 2020. The relationship between average grip strength and knee pain in 2011 were analyzed, and follow up was conducted on the occurrence of knee joint pain. According to whether the knee joint is painful, the population who participated in the “Knee Joint Pain Symptoms” survey in 2011 were divided into the knee joint pain free group and the knee joint pain group. According to the follow-up data, the population who participated in the “Knee Pain Symptoms” survey in 2011 and had no knee pain were divided into a group without knee pain and a group with knee pain. Use logistic regression to analyze the correlation between average grip strength and knee pain. Apply a restrictive cubic spline model to analyze the dose-response relationship between average grip strength and knee joint pain occurrence. ResultsA total of 12 307 cases were included in 2011. The results of multiple logistic regression analysis showed that average grip strength was associated with knee joint pain. The incidence of knee joint pain increases with a decrease in average grip strength. During the 9-year follow-up period, a total of 9 667 cases were included. The results of multiple logistic regression analysis showed that average grip strength was correlated with the occurrence of knee joint pain. Compared to the group with the highest average grip strength, the low grip strength group had an increased risk of developing knee joint pain. The results of the restricted cubic spline analysis showed that the continuous changes in average grip strength were strongly correlated with knee joint pain in a linear dose-response relationship. As the average grip strength level increases, the incidence of knee joint pain decreases. Conclusion There is a correlation between average grip strength and knee joint pain. The risk of knee joint pain is higher with low average grip strength.
