Tuberculosis (TB), caused by Mycobacterium tuberculosis (MTB), is a serious infectious disease that poses a significant threat to public health security. Rapid, sensitive and accurate diagnosis of TB is of vital importance. Omics, by analyzing genes, proteins, metabolites and other components in biological samples, reveals the functional status and changes of biological systems, providing new perspectives and tools for the diagnosis of TB. This article reviews the application and progress of omics in the diagnosis of TB, including the application of genomics, transcriptomics, proteomics, metabolomics and lipidomics, offering new ideas and directions for omics-based methods in TB diagnosis.
