Large-for-size syndrome (LFSS) is a fatal complication of abdominal and thoracic organ compression due to mismatch of the size of the graft and recipient abdominal cavity. In recent years, with the increased prevalence of obesity epidemic among the donor pool, the incidence of LFSS tends to increase in adult liver transplantation. However, it is still unclear how to effectively prevent LFSS after adult death after citizen death (DCD) liver transplantation. Almost all transplantation centers rely on experience to deal with it, and there is no objective prevention strategy. This article summarizes the current problems in preventing LFSS after adult DCD liver transplantation, and our team’s exploration of the existing problems.
