Objective
To summarize the current research advances of colorectal signet-ring cell carcinoma (SRCC).
Methods
In this paper, the related literatures of colorectal SRCC in recent years were collected and reviewed.
Results
Colorectal SRCC was a pathological subtype of colorectal adenocarcinoma, with extremely low incidence but high malignancy and poor prognosis. At present, its molecular mechanism was still not very clear and the clinicopathological manifestations were not specific. Surgical treatment was the major treatmen.
Conclusions
Although we already have a certain degree of understanding about colorectal SRCC, due to the limitations in the results of some related researches because of the small sample size or the single-center study, we still need more researches to improve the cognition of colorectal SRCC.
