ObjectiveTo summarize the mid-term outcomes and surgical experience of transthoracic device closure for doubly committed subarterial ventricular septal defect (dcsVSD) in our center. MethodsPatients with dcsVSD who underwent transthoracic device closure in the Department of Cardiovascular Surgery, West China Hospital, Sichuan University, from January 2013 to October 2025 were retrospectively enrolled. Baseline characteristics, perioperative data, and follow-up data were analyzed. ResultsA total of 68 patients were enrolled, including 35 (52.9%) males and 33 (47.1%) females, with a median age of 1.8 (1.0, 3.0) years and a median VSD diameter of 4.0 (3.0, 5.0) mm. The defects were successfully closed using eccentric VSD occluders in all patients, with a median operative time of 24.0 (20.0, 40.0) min and a median eccentric VSD occluder diameter of 7.0 (6.0, 8.0) mm. The median follow-up duration was 59.0 (29.5, 74.3) months. New-onset aortic regurgitation during follow-up was observed in 5 (7.4%) patients, among whom 1 patient underwent reoperation. No patient had residual shunt at the latest follow-up. No occluder displacement, new-onset atrioventricular block, or left/right ventricular outflow tract obstruction occurred during the follow-up. ConclusionTransthoracic device closure for dcsVSD yields relatively satisfactory mid-term outcomes. Meticulous preoperative evaluation and more stringent patient selection are crucial to avoid new-onset aortic regurgitation during the follow-up.