Objective To investigate the characteristics of multifocal visual evoked potential (mf-VEP) in healthy individuals, and provide normal reference values for its clinical application. Methods The mf-VEP of 37 healthy individuals (70 eyes) were examined by VERIS ScienceTM4.0. The visual stimulus was adart board with patterns consisted of 60 patches spanning a 25°visual field. The length of m-sequence was 214-1. The results were recorded by bipolar occipital straddle. The signal was amplified 100 K and was put through a band-pass filter between 3 and 100 Hz. The first slice of the second order kernel was analyzed by VERIS software. The summed responses of fields with different stimulus were a nalyzed and compared according to different ages, genders and eyes.Results The latencies and response densities of amplitude had statistically significant differences both in dimidiate and quartered field（Plt;0.05）. The latencies in ≥50 year group were much more delayed in some sectors of the visual field than those in lt; 50 year group（Plt;0.05）. The latencies of women were shorter than those of men（Plt;0.05）. There was no obvious difference of latencies and response densities of amplitude in each field sectors between both eyes（Pgt;0.05）. Conclusions The mf-VEP of healthy individuals can reflect the VEP at different field ocations objectively with its specific physiological characteristics, which may provide normal reference values for its clinical application.(Chin J Ocul Fundus Dis，2003，19：269-332)
