MRI常規掃描及彌散加權成像在宮頸癌評價中的價值_West China Medical Journal

Authors：

 李玉明 ¹ , 唐鶴涵 ¹ , 李真林 ¹ ,  程燕 ²

1. ;
2. ;

Corresponding?author：

程燕, Email: yanchee@qq.com

Keywords：

磁共振成像; 常規掃描; 彌散加權成像; 宮頸癌

DOI：

10.7507/1002-0179.20150341

Video：

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MRI常規掃描憑借著較高的軟組織分辨率對宮頸癌腫塊在宮頸內部的生長情況、腫塊對宮體的侵犯程度以及對宮旁癌周的侵犯、宮旁閉孔區淋巴結轉移的評價方面具有較高準確性和特異性。MRI常規掃描可提高宮頸癌的定位、定性、分期的準確性，有助于臨床國際婦產科聯盟（FIGO）分期。MRI彌散加權成像，作為功能磁共振的一種，是唯一一種可以評價活體組織內水分子彌散狀況的掃描方法，利用彌散加權成像獲得表觀彌散系數值可以對宮頸癌病灶組織病理學類型及分化程度、宮旁侵犯、淋巴結轉移進行定量定性分析。將彌散加權成像與常規掃描結合起來在診斷宮頸癌、協助臨床FIGO分期、制訂優化個體化治療方案及預后預測上有較大臨床應用價值。

Citation： 李玉明, 唐鶴涵, 李真林, 程燕. MRI常規掃描及彌散加權成像在宮頸癌評價中的價值. West China Medical Journal, 2015, 30(6): 1183-1186. doi: 10.7507/1002-0179.20150341 Copy

1.	李霓, 鄭榮壽, 張思維, 等. 2003~2007年中國宮頸癌發病與死亡分析[J]. 中國腫瘤, 2012, 21(11):801-804.
2.	黃永剛, 帥茨霞, 胡燕. 宮頸癌年輕化發病相關因素研究進展[J]. 國外醫學:婦產科學分冊, 2005, 32(3):186-189.
3.	姜艷. 宮頸癌發病年輕化趨勢的研究現狀[J]. 醫學綜述, 2012, 18(24):4166-4169.
4.	Haggar FA, Preen DB, Pereira G, et al. Cancer incidence and mortality trends in Australian adolescents and young adults, 1982-2007[J]. BMC Cancer, 2012, 20(12):151.
5.	Eifel PJ, Berek JS, Thigpen JT. Cancer of the cervix vagina, and vulva[C]//DeVitaVT, Philadelphia, Pa:Lippineott, 1997:1433-1475.
6.	Subak LL, Hricak H, Powell CB, et al. Cervical carcinoma:computed tomography and magnetic resonance imaging for preoperative staging[J]. Obstet Gynecol, 1995, 86(1):43-50.
7.	Fischerová D, Cibula D, Stenhová H, et al. Use of transrectal ultrasound and magnetic resonance imaging in the staging of early-stage cervical cancer[J]. Ceská Gynekol, 2009, 74(5):323-329.
8.	張靜, 袁小東, 王培軍. 1.5 T磁共振對宮頸癌手術可切除性判斷的準確性分析[J]. 中國醫學計算機成像雜志, 2012, 18(5):412-414.
9.	Nicolet V, Carignan L, Bourdon F, et al. Mr imaging of cervical carcinoma:a practical staging approach[J]. Radiographics, 2001, 20(6):1539-1549.
10.	江新青, 謝琦, 梁長虹, 等. 宮頸癌的MRI診斷與分期研究[J]. 中華放射學雜志, 2002, 36(7):621-625.
11.	Stenstedt K, Hellstr?m AC, Fridsten S, et al. Impact of MRI in the management and staging of cancer of the uterine cervix[J]. Acta Oncol, 2011, 50(3):420-426.
12.	Yasuda S, Kojima A, Maeno Y, et al. Poor prognosis of patients with stage Ⅰb1 adenosquamous cell carcinoma of the uterine cervix with pelvic lymphnode metastasis[J]. Kobe J Med Sci, 2006, 52(1/2):9-15.
13.	Hashimoto I, Kodama J, Seki N, et al. Vascular endothelial growth factor-C expression and its relationship to pelvic lymph node status in invasive cervical cancer[J]. Br J Cancer, 2001, 85(1):93-97.
14.	Scheidler JJ, Hricak H, Yu KK, et al. Radiological evaluation of lymph node metastases in patients with cervical cancer: a metaanalysis[J]. JAMA, 1997, 278(13):1096-1101.
15.	李燕, 王鑾虹, 朱安娜, 等. Ⅰ B1~Ⅱ B期宮頸癌盆腔淋巴結轉移的分布特點及其對預后的影響[J]. 實用婦產科雜志, 2013, 29(8):598-602.
16.	Chung HH, Kang SB, Cho JY, et al. Can preoperative MRI accurately evaluate nodal and parametrial invasion in early stage cervical cancer?[J]. Jpn J Clin Oncol, 2007, 37(5):370-375.
17.	Hancke K, Heilmann V, Straka P, et al. Pretreatment staging of cervical cancer:is imaging better than palpation? Role of CT and MRI in preoperative staging of cervical cancer:single institution results for 255 patients[J]. Ann Surg Oncol, 2008, 15(10):2856-2861.
18.	Sahdev A, Sohaib SA, Wenaden AE, et al. The performance of magnetic resonance imaging in early cervical carcinoma:a long-term experience[J]. Int J Gynecol Cancer, 2007, 17(3):629-636.
19.	Lam WW, So NM, Yang WT, et al. Detection of parametrial invasion in cervical carcinoma:role of short tau inversion recovery sequence[J]. Clin Radiol, 2000, 55(9):702-707.
20.	Taouli B, Koh DM. Diffusion-weighted Mr imaging of the liver[J]. Radiology, 2010, 254(1):47-66.
21.	McVeigh PZ, Syed AM, Milosevic M, et al. Diffusion-weighted MRI in cervical cancer[J]. Eur Radiol, 2008, 18(5):1058-1064.
22.	Brisigotti M, Cozzutto C, Fabbretti G, et al. Metanephric adenoma[J]. Histol Histopathol, 1992, 7(4):689-692.
23.	Naganawa S, Sato C, Kumada H, et al. Apparent diffusion coefficient in cervical cancer of the uterus:comparison with the normal uterine cervix[J]. Eur Radiol, 2005, 15(1):71-78.
24.	Liu Y, Bai R, Sun H, et al. Diffusion-weighted magnetic resonance imaging of uterine cervical cancer[J]. J Comput Assist Tomogr, 2009, 33(6):858-862.
25.	張赟, 梁碧玲, 高立, 等. 正常子宮頸和宮頸癌的彌散加權成像特點[J]. 癌癥, 2007, 26(5):508-512.
26.	賀李, 余深平, 莊曉曌, 等. 子宮頸癌3.0 T磁共振彌散加權成像與病理的初步相關研究[J]. 中華臨床醫師雜志:電子版, 2011, 5(2):363-367.
27.	Hoogendam JP, Klerkx WM, De Kort GA, et al. The influence of the b-value combination on apparent diffusion coefficient based differentiation between malignant and benign tissue in cervical cancer[J]. J Magn Reson Imaging, 2010, 32(2):376-382.
28.	Chen YB, Hu CM, Chen GL, et al. Staging of uterine cervical carcinoma:whole-body diffusion-weighted magnetic resonance imaging[J]. Abdom Imaging, 2011, 36(5):619-626.
29.	Andrews RT, Brown PH. Uterine arterial embolization:factors influencing patient radiation exposure[J]. Radiology, 2000, 217(3):713-722.
30.	Liu S, Semenciw R, Probert A, et al. Cervical cancer in Canada:changing patterns in incidence and mortality[J]. Int J Gynecol Cancer, 2001, 11(1):24-31.
31.	Kuang F, Ren J, Zhong Q, et al. The value of apparent diffusion coefficient in the assessment of cervical cancer[J]. Eur Radiol, 2013, 23(4):1050-1058.
32.	Yu SP, He L, Liu B, et al. Differential diagnosis of metastasis from non-metastatic lymph nodes in cervical cancers:pilot study of diffusion weighted imaging with background suppression at 3T magnetic resonance[J]. Chin Med J (Engl), 2010, 123(20):2820-2824.
33.	Xue HD, Li S, Sun F, et al. Clinical application of body diffusion weighted Mr imaging in the diagnosis and preoperative N staging of cervical cancer[J]. Chin Med Sci J, 2008, 23(3):133-137.
34.	Lin G, Ho KC, Wang JJ, et al. Detection of lymph node metastasis in cervical and uterine cancers by diffusion-weighted magnetic resonance imaging at 3T[J]. J Magn Reson Imaging, 2008, 28(1):128-135.

1. 李霓, 鄭榮壽, 張思維, 等. 2003~2007年中國宮頸癌發病與死亡分析[J]. 中國腫瘤, 2012, 21(11):801-804.
2. 黃永剛, 帥茨霞, 胡燕. 宮頸癌年輕化發病相關因素研究進展[J]. 國外醫學:婦產科學分冊, 2005, 32(3):186-189.
3. 姜艷. 宮頸癌發病年輕化趨勢的研究現狀[J]. 醫學綜述, 2012, 18(24):4166-4169.
4. Haggar FA, Preen DB, Pereira G, et al. Cancer incidence and mortality trends in Australian adolescents and young adults, 1982-2007[J]. BMC Cancer, 2012, 20(12):151.
5. Eifel PJ, Berek JS, Thigpen JT. Cancer of the cervix vagina, and vulva[C]//DeVitaVT, Philadelphia, Pa:Lippineott, 1997:1433-1475.
6. Subak LL, Hricak H, Powell CB, et al. Cervical carcinoma:computed tomography and magnetic resonance imaging for preoperative staging[J]. Obstet Gynecol, 1995, 86(1):43-50.
7. Fischerová D, Cibula D, Stenhová H, et al. Use of transrectal ultrasound and magnetic resonance imaging in the staging of early-stage cervical cancer[J]. Ceská Gynekol, 2009, 74(5):323-329.
8. 張靜, 袁小東, 王培軍. 1.5 T磁共振對宮頸癌手術可切除性判斷的準確性分析[J]. 中國醫學計算機成像雜志, 2012, 18(5):412-414.
9. Nicolet V, Carignan L, Bourdon F, et al. Mr imaging of cervical carcinoma:a practical staging approach[J]. Radiographics, 2001, 20(6):1539-1549.
10. 江新青, 謝琦, 梁長虹, 等. 宮頸癌的MRI診斷與分期研究[J]. 中華放射學雜志, 2002, 36(7):621-625.
11. Stenstedt K, Hellstr?m AC, Fridsten S, et al. Impact of MRI in the management and staging of cancer of the uterine cervix[J]. Acta Oncol, 2011, 50(3):420-426.
12. Yasuda S, Kojima A, Maeno Y, et al. Poor prognosis of patients with stage Ⅰb1 adenosquamous cell carcinoma of the uterine cervix with pelvic lymphnode metastasis[J]. Kobe J Med Sci, 2006, 52(1/2):9-15.
13. Hashimoto I, Kodama J, Seki N, et al. Vascular endothelial growth factor-C expression and its relationship to pelvic lymph node status in invasive cervical cancer[J]. Br J Cancer, 2001, 85(1):93-97.
14. Scheidler JJ, Hricak H, Yu KK, et al. Radiological evaluation of lymph node metastases in patients with cervical cancer: a metaanalysis[J]. JAMA, 1997, 278(13):1096-1101.
15. 李燕, 王鑾虹, 朱安娜, 等. Ⅰ B1~Ⅱ B期宮頸癌盆腔淋巴結轉移的分布特點及其對預后的影響[J]. 實用婦產科雜志, 2013, 29(8):598-602.
16. Chung HH, Kang SB, Cho JY, et al. Can preoperative MRI accurately evaluate nodal and parametrial invasion in early stage cervical cancer?[J]. Jpn J Clin Oncol, 2007, 37(5):370-375.
17. Hancke K, Heilmann V, Straka P, et al. Pretreatment staging of cervical cancer:is imaging better than palpation? Role of CT and MRI in preoperative staging of cervical cancer:single institution results for 255 patients[J]. Ann Surg Oncol, 2008, 15(10):2856-2861.
18. Sahdev A, Sohaib SA, Wenaden AE, et al. The performance of magnetic resonance imaging in early cervical carcinoma:a long-term experience[J]. Int J Gynecol Cancer, 2007, 17(3):629-636.
19. Lam WW, So NM, Yang WT, et al. Detection of parametrial invasion in cervical carcinoma:role of short tau inversion recovery sequence[J]. Clin Radiol, 2000, 55(9):702-707.
20. Taouli B, Koh DM. Diffusion-weighted Mr imaging of the liver[J]. Radiology, 2010, 254(1):47-66.
21. McVeigh PZ, Syed AM, Milosevic M, et al. Diffusion-weighted MRI in cervical cancer[J]. Eur Radiol, 2008, 18(5):1058-1064.
22. Brisigotti M, Cozzutto C, Fabbretti G, et al. Metanephric adenoma[J]. Histol Histopathol, 1992, 7(4):689-692.
23. Naganawa S, Sato C, Kumada H, et al. Apparent diffusion coefficient in cervical cancer of the uterus:comparison with the normal uterine cervix[J]. Eur Radiol, 2005, 15(1):71-78.
24. Liu Y, Bai R, Sun H, et al. Diffusion-weighted magnetic resonance imaging of uterine cervical cancer[J]. J Comput Assist Tomogr, 2009, 33(6):858-862.
25. 張赟, 梁碧玲, 高立, 等. 正常子宮頸和宮頸癌的彌散加權成像特點[J]. 癌癥, 2007, 26(5):508-512.
26. 賀李, 余深平, 莊曉曌, 等. 子宮頸癌3.0 T磁共振彌散加權成像與病理的初步相關研究[J]. 中華臨床醫師雜志:電子版, 2011, 5(2):363-367.
27. Hoogendam JP, Klerkx WM, De Kort GA, et al. The influence of the b-value combination on apparent diffusion coefficient based differentiation between malignant and benign tissue in cervical cancer[J]. J Magn Reson Imaging, 2010, 32(2):376-382.
28. Chen YB, Hu CM, Chen GL, et al. Staging of uterine cervical carcinoma:whole-body diffusion-weighted magnetic resonance imaging[J]. Abdom Imaging, 2011, 36(5):619-626.
29. Andrews RT, Brown PH. Uterine arterial embolization:factors influencing patient radiation exposure[J]. Radiology, 2000, 217(3):713-722.
30. Liu S, Semenciw R, Probert A, et al. Cervical cancer in Canada:changing patterns in incidence and mortality[J]. Int J Gynecol Cancer, 2001, 11(1):24-31.
31. Kuang F, Ren J, Zhong Q, et al. The value of apparent diffusion coefficient in the assessment of cervical cancer[J]. Eur Radiol, 2013, 23(4):1050-1058.
32. Yu SP, He L, Liu B, et al. Differential diagnosis of metastasis from non-metastatic lymph nodes in cervical cancers:pilot study of diffusion weighted imaging with background suppression at 3T magnetic resonance[J]. Chin Med J (Engl), 2010, 123(20):2820-2824.
33. Xue HD, Li S, Sun F, et al. Clinical application of body diffusion weighted Mr imaging in the diagnosis and preoperative N staging of cervical cancer[J]. Chin Med Sci J, 2008, 23(3):133-137.
34. Lin G, Ho KC, Wang JJ, et al. Detection of lymph node metastasis in cervical and uterine cancers by diffusion-weighted magnetic resonance imaging at 3T[J]. J Magn Reson Imaging, 2008, 28(1):128-135.

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MRI常規掃描及彌散加權成像在宮頸癌評價中的價值

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