RISKS AND CONTROL OF DISEASES TRANSMISSION IN TRANSPLANTAION OF HUMAN ALLOGENIC BONE_Chinese Journal of Reparative and Reconstructive Surgery

Authors：

LIJing ,  CHENXueying

Shanxi Provincial Tissue Bank, Taiyuan Shanxi, 030006, P. R. China;

Corresponding?author：

CHENXueying, Email: xycc140@yeah.net

Keywords：

Allogenic bone; Disease transmission; Risk; Control

DOI：

10.7507/1002-1892.20150139

Video：

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Objective To review the risks and control of disease transmission in clinical transplantation of human allogenic bone. Methods The related literature on diseases transmission, risks and control, and tissue banking technology in human allogenic bone application was extensively reviewed and analyzed. Results The tissue is not sterilized in transmission cases relative to human allogenic bone transplantation reported abroad. While no transmission case was reported domestically because of final sterilization and strict performance during preparation. Conclusion Strict standard operation, virus inactivation, and final sterilization could effectively control the risks of diseases transmission in human allogenic bone transplantation.

Citation： LIJing, CHENXueying. RISKS AND CONTROL OF DISEASES TRANSMISSION IN TRANSPLANTAION OF HUMAN ALLOGENIC BONE. Chinese Journal of Reparative and Reconstructive Surgery, 2015, 29(5): 649-651. doi: 10.7507/1002-1892.20150139 Copy

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1. 李寶興. 同種組織移植與組織庫. 北京:原子能出版社, 2010:73.
2. 宋會平, 王志強. 異體骨的臨床應用. 中國修復重建外科雜志, 2006, 20(1):77-80.
3. 劉斌. 同種異體骨的易感疾病風險與控制. 中國矯形外科雜志, 2009, 17(15):1164-1169.
4. 許偉. 同種骨應用中的風險與管理. 中國醫療器械信息, 2009, 15(12):6-9.
5. 孫世荃, 李寶興. 同種異體骨移植引起的疾病傳播. 中國骨腫瘤骨病, 2003, 2(6):333-335.
6. Simonds RJ, Holmberg SD, Hurwitz RL, et al. Transmission of human immunodeficiency virus type 1 from a seronegative organ and tissue donor. N Engl J Med, 1992, 326(11):726-732.
7. Conrad EU, Gretch DR, Obermeyer KR, et al. Transmission of the hepatitis C virus by tissue transplantation. J Bone Joint Surg (Am), 1995, 77(2):214-224.
8. 同種組織移植物生產技術要求(Q/DS. J4001-2007). 太原:山西省醫用組織庫, 2007.
9. 國家質量技術監督局. 中華人民共和國國家標準:GB18280-2007醫療保健產品滅菌-輻射. 北京:中國標準出版社, 2007.

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Chinese Journal of Reparative and Reconstructive Surgery

RISKS AND CONTROL OF DISEASES TRANSMISSION IN TRANSPLANTAION OF HUMAN ALLOGENIC BONE

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