Expert consensus on diagnosis and treatment of spina bifida_Chinese Journal of Reparative and Reconstructive Surgery

Authors：

 Spina Bifida Group of Professional Rehabilitation Committee of Disabled Limbs & Trunk of China ?

Corresponding?author：

Spina Bifida Group of Professional Rehabilitation Committee of Disabled Limbs & Trunk of China ?, Email: boxiu@scsurgery.com

Keywords：

Spina bifida; tethered spinal cord; expert consensus; diagnosis; treatment

DOI：

10.7507/1002-1892.202105099

Video：

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Abstract Full text Figures/Tables Video References Cited by

Spina bifida and tethered spinal cord are congenital diseases that can lead to severe disability. At present, most doctors in relevant specialties in China still have insufficient understanding of spina bifida, resulting in high incidence and aggravation of its complications. To provide guidance for the diagnosis and treatment of spina bifida and tethered spinal cord in China, experts from neurosurgery, urology, orthopedics, spine surgery, and rehabilitation departments who have experiences in the diagnosis and treatment of spina bifida discussed and summarized their experiences, and referred to the relevant literature on the diagnosis and treatment of spina bifida at home and abroad. Expert consensus was formed in the following aspects: concept, classification, and pathological changes of spina bifida; diagnosis; treatment process and operation timing; principles and methods of treatment; rehabilitation; and follow up. This expert consensus can provide reference for relevant care providers of spina bifida in China.

Citation： Spina Bifida Group of Professional Rehabilitation Committee of Disabled Limbs & Trunk of China ?. Expert consensus on diagnosis and treatment of spina bifida. Chinese Journal of Reparative and Reconstructive Surgery, 2021, 35(11): 1361-1367. doi: 10.7507/1002-1892.202105099 Copy

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2. Castill J, Castillo H, Brei TJ. Guidelines and scientifically-based spina bifida care: Guidance across the lifespan in a global health context. J Pediatr Rehabil Med, 2020, 13(4): 453-455.
3. Ryznychuk MO, Kryvchanska MI, Lastivka IV, et al. Incidence and risk factors of spina bifida in children. Wiad Lek, 2018, 71(2 pt 2): 339-344.
4. Atta CA, Fiest KM, Frolkis AD, et al. Global birth prevalence of spina bifida by folic acid fortification status: A systematic review and meta-analysis. Am J Public Health, 2016, 106(1): e24-e34.
5. D’Antoine H, Bower C. Folate status and neural tube defects in aboriginal Australians: the success of mandatory fortification in reducing a health disparity. Curr Dev Nutr, 2019, 3(8): nzz071. doi: 10.1093/cdn/nzz071.
6. 王欣業, 李采青, 王義成, 等. 神經管畸形發病率及相關預防措施的探討. 河北醫藥, 2010, 32(21): 3058-3059.
7. Liu J, Xie J, Li Z, et al. Sex differences in the prevalence of neural tube defects and preventive effects of folic acid (FA) supplementation among five counties in northern China: results from a population-based birth defect surveillance programme. BMJ Open, 2018, 8 (11): e022565. doi: 10.1136/bmjopen-2018-022565.
8. Ye RW, Li S, Zheng JC, et al. Prevalence of neural tube defects at birth in 30 counties and cities of China, 1993-2000. 北京大學學報(醫學版), 2002, 34(3): 204-209.
9. 臧建成. 號角吹響使命在肩——記中國殘疾人康復協會肢體殘疾康復專委會“脊柱裂學組”成立. 中國矯形外科雜志, 2019, 27(22): 2111-2112.
10. 修波. 應重視規范脊神經管畸形的分型. 中華醫學雜志, 2017, 97(48): 3761-3762.
11. 修波. 實用脊神經管畸形分型及其臨床意義. 中華神經外科疾病研究雜志, 2017, 16(5): 393-396.
12. Blount JP, Bowman R, Dias MS, et al. Neurosurgery guidelines for the care of people with spina bifida. J Pediatr Rehabil Med, 2020, 13(4): 467-477.
13. Beierwaltes P. Guidelines for the care of people with spina bifida. J Pediatr Nurs, 2019, 45: 81-82.
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16. Jones V, Wykes V, Cohen N, et al. The pathology of lumbosacral lipomas: macroscopic and microscopic disparity have implications for embryogenesis and mode of clinical deterioration. Histopathology, 2018, 72(7): 1136-1144.
17. Jones V, Thompson D. Placode rotation in transitional lumbosacral lipomas: are there implications for origin and mechanism of deterioration? Childs Nerv Syst, 2018, 34(8): 1557-1562.
18. 崔志強, 孫振興, 蕭凱, 等. 脊髓脊膜膨出合并腦積水手術方式的分析. 中華神經外科雜志, 2014, 30(2): 147-150.
19. 張春梅. 超聲診斷胎兒脊柱裂的價值及鑒別診斷開放性脊柱裂和閉合性脊柱裂的實用效果分析. 系統醫學, 2018, 3(1): 12-14.
20. 朱晨, 任蕓蕓, 嚴英榴, 等. 胎兒開放性脊柱裂和閉合性脊柱裂的超聲鑒別診斷. 復旦學報 (醫學版), 2016, 43(2): 195-200.
21. 楊培枝. 產前容積超聲定位胎兒圓錐末端價值. 山西醫藥雜志, 2019, 48(4): 431-432.
22. 司丕成, 曾憲良, 劉福云, 等. 新生兒脊髓圓錐末端位置的B超研究. 臨床小兒外科雜志, 2007, 6(1): 19-21.
23. 胡海云, 張蒂榮, 王玥, 等. 超聲定位中晚孕期胎兒脊髓圓錐位置. 中國醫學影像技術, 2013, 29(5): 779-782.
24. 修波. 脊柱裂研究進展. 中華神經外科疾病研究雜志, 2017, 16(2): 97-100.
25. 蔡明, 劉建民, 修波. 無癥狀兒童脊髓栓系早期預防性手術治療研究. 中華神經外科疾病研究雜志, 2016, 15(1): 62-65.
26. Shang AJ, Yang CH, Cheng C, et al. Microsurgical efficacy in 326 children with tethered cord syndrome: a retrospective analysis. Neural Regen Res, 2019, 14(1): 149-155.
27. Morioka T, Murakami N, Shimogawa T, et al. Neurosurgical management and pathology of lumbosacral lipomas with tethered cord. Neuropathology, 2017, 37(5): 385-392.
28. Seki T, Hida K, Yano S, et al. Surgical outcomes of pediatric patients with asymptomatic tethered cord syndrome. Asian Spine J, 2018, 12(3): 551-555.
29. 蕭凱, 孫振興, 修波, 等. 嬰幼兒脊髓脊膜膨出術后并發腦積水的影響因素及治療方法分析. 中國微侵襲神經外科雜志, 2012, 17(9): 400-402.
30. 崔志強, 修波. 脊膜膨出術后并發良性顱內壓增高23例臨床分析. 北京醫學, 2011, 33(5): 374-376.
31. Aufschnaiter K, Fellner F, Wurm G. Surgery in adult onset tethered cord syndrome (ATCS): review of literature on occasion of an exceptional case. Neurosurg Rev, 2008, 31(4): 371-383.
32. 修波, 李萃萃, 李文德, 等. 脊髓脂肪瘤的診治策略. 中華神經醫學雜志, 2020, 19(7): 725-728.
33. 修波, 李萃萃, 林和璞, 等. 顯微外科手術治療403例脂肪脊髓脊膜膨出療效分析. 中華神經醫學雜志, 2018, 17(7): 720-722.
34. Pang D. Surgical management of complex spinal cord lipomas: A new perspective. J Korean Neurosurg Soc, 2020, 63(3): 279-313.
35. Pang D. Surgical management of complex spinal cord lipomas: how, why, and when to operate. A review. J Neurosurg Pediatr, 2019, 23(5): 537-556.
36. Xiu Bo, Liu Fuyun, Shang Aijia, et al. Chinese expert consensus on diagnosis and management of split cord malformation. Journal of Neurorestoratology, 2020, 8(2): 83-92.
37. 修波. 脊髓縱裂診治中的常見問題及其對策. 臨床小兒外科雜志, 2019, 18(2): 83-87.
38. Joseph DB, Baum MA, Tanaka ST, et al. Urologic guidelines for the care and management of people with spina bifida. J Pediatr Rehabil Med, 2020, 13(4): 479-489.
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