Clinical Research on Intracavity Laser Combining with Poly Cinnamyl Alcohol Foam Hardener in Treatment of Lower Extremity Varicose Veins_CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

Authors：

 李文仿 , 周科 , 周坤 ,  趙宗彬

湖北醫藥學院附屬太和醫院普三科（湖北十堰 442000）;

Corresponding?author：

趙宗彬, Email: zzb54@sina.com

Keywords：

腔內激光; 泡沫硬化療法; 靜脈曲張; 療效

DOI：

10.7507/1007-9424.20140370

Video：

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目的觀察腔內激光聯合聚桂醇泡沫硬化劑治療下肢靜脈曲張的臨床效果。方法回顧性分析2009年2月至2013年7月期間接受腔內激光聯合聚桂醇泡沫硬化劑治療的40例下肢靜脈曲張患者（聯合組）和單純接受腔內激光治療的40例下肢靜脈曲張患者（對照組）的臨床資料，比較2種治療方法的效果。結果聯合組和對照組患者的手術時間〔（43.95±6.77）min比（45.20±6.77）min〕和術中出血量〔（16.07±4.30）mL比（16.65±4.50）mL〕比較差異均無統計學意義（P＞0.05），但聯合組的手術費用低于對照組〔（7 056.83±940.45）元比（7 473.81±1 476.09）元〕，P=0.044。術后對照組的并發癥發生率為20.0%（8/40），高于聯合組的5.0%（1/40），差異有統計學意義（P=0.029）。術后所有患者獲訪4～24個月、（15.5±6.7）個月。隨訪期間，80例患者的下肢曲張畸形靜脈均消失，對照組小范圍復發3例（7.5%），聯合組小范圍復發2例（5.0%），2組復發率的差異無統計學意義（P=1.000）。結論對下肢靜脈曲張，腔內激光聯合泡沫硬化劑治療是一種安全和有效的新微創手術方法，具有并發癥發生率低的優點，值得臨床推廣。

Citation： 李文仿, 周科, 周坤, 趙宗彬. Clinical Research on Intracavity Laser Combining with Poly Cinnamyl Alcohol Foam Hardener in Treatment of Lower Extremity Varicose Veins. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2014, 21(12): 1564-1566. doi: 10.7507/1007-9424.20140370 Copy

1.	Moul DK, Housman L, Romine S, et al.Endovenous laser ablation of the great and short saphenous veins with a 1320-nm neodymium:yttrium-aluminum-garnet laser:retrospective case series of 1171 procedures[J].J Am Acad Dermatol, 2014, 70(2):326-331.
2.	袁鏈, 尹立偉, 張小明.早期小切口大隱靜脈高位結扎剝脫術治療伴急性血栓性淺靜脈炎的大隱靜脈曲張[J].中國微創外科雜志, 2013, 13(3):246-248.
3.	史建中.大隱靜脈高位結扎聯合腔內激光閉合術治療下肢靜脈曲張319例臨床分析[J].中國現代普通外科進展, 2011, 14(10):828-829.
4.	Shadid NH, van der Velden SK, van Oerle R, et al.In vivo effects of foam sclerotherapy on coagulation[J].Phlebology, 2013, 29(5):287-292.
5.	陳建華, 楊偉剛, 季曉亮, 等.腔內激光治療下肢靜脈曲張56例[J].中國中西醫結合外科雜志, 2013, 19(2):205-206.
6.	Samuel N, Wallace T, Carradice D, et al.Comparison of 12-w versus 14-w endovenous laser ablation in the treatment of great saphenous varicose veins:5-year outcomes from a randomized controlled trial[J].Vasc Endovascular Surg, 2013, 47(5):346-352.
7.	Chen JQ, Xie H, Deng HY, et al.Endovenous laser ablation of great saphenous vein with ultrasound-guided perivenous tumescence:early and midterm results[J].Chin Med J (Engl), 2013, 126(3):421-425.
8.	Biemans AA, Kockaert M, Akkersdijk GP, et al.Comparing endovenous laser ablation, foam sclerotherapy, and conventional surgery for greatsaphenous varicose veins[J].J Vasc Surg, 2013, 58(3):727-734.
9.	Bozoglan O, Mese B, Inci MF, et al.A rare complication of endovenous laser ablation:intravascular laser catheter breakage[J].BMJ Case Rep, 2013.
10.	Duman E, Yildirim E, Saba T, et al.The effect of laser wavelength on postoperative pain score in the endovenous ablation of saphenous vein insufficiency[J].Diagn Interv Radiol, 2013, 19(4):326-329.
11.	龔凱, 黃道景, 張亞明, 等.腔內激光與腔內激光聯合泡沫硬化劑治療下肢靜脈曲張的比較研究[J].中國微創外科雜志, 2012, 12(7):601-603.
12.	馮蘇, 田志龍, 賈高磊, 等.限制性內翻剝脫聯合TriVex旋切及泡沫硬化劑治療下肢靜脈曲張(附132例報告)[J].中國微創外科雜志, 2014, 14(2):151-154.
13.	Burihan MC.Endovenous ablation (radiofrequency and laser) and foam sclerotherapy versus conventional surgery for great saphenous vein varices[J].Sao Paulo Med J, 2014, 132(1):69.
14.	Badri H, Bhattacharya V.A review of current treatment strategies for varicose veins[J].Recent Pat Cardiovasc Drug Discov, 2008, 3(2):126-136.
15.	Coleridge Smith P.Sclerotherapy and foam sclerotherapy for varicose veins[J].Phlebology, 2009, 24(6):260-269.

1. Moul DK, Housman L, Romine S, et al.Endovenous laser ablation of the great and short saphenous veins with a 1320-nm neodymium:yttrium-aluminum-garnet laser:retrospective case series of 1171 procedures[J].J Am Acad Dermatol, 2014, 70(2):326-331.
2. 袁鏈, 尹立偉, 張小明.早期小切口大隱靜脈高位結扎剝脫術治療伴急性血栓性淺靜脈炎的大隱靜脈曲張[J].中國微創外科雜志, 2013, 13(3):246-248.
3. 史建中.大隱靜脈高位結扎聯合腔內激光閉合術治療下肢靜脈曲張319例臨床分析[J].中國現代普通外科進展, 2011, 14(10):828-829.
4. Shadid NH, van der Velden SK, van Oerle R, et al.In vivo effects of foam sclerotherapy on coagulation[J].Phlebology, 2013, 29(5):287-292.
5. 陳建華, 楊偉剛, 季曉亮, 等.腔內激光治療下肢靜脈曲張56例[J].中國中西醫結合外科雜志, 2013, 19(2):205-206.
6. Samuel N, Wallace T, Carradice D, et al.Comparison of 12-w versus 14-w endovenous laser ablation in the treatment of great saphenous varicose veins:5-year outcomes from a randomized controlled trial[J].Vasc Endovascular Surg, 2013, 47(5):346-352.
7. Chen JQ, Xie H, Deng HY, et al.Endovenous laser ablation of great saphenous vein with ultrasound-guided perivenous tumescence:early and midterm results[J].Chin Med J (Engl), 2013, 126(3):421-425.
8. Biemans AA, Kockaert M, Akkersdijk GP, et al.Comparing endovenous laser ablation, foam sclerotherapy, and conventional surgery for greatsaphenous varicose veins[J].J Vasc Surg, 2013, 58(3):727-734.
9. Bozoglan O, Mese B, Inci MF, et al.A rare complication of endovenous laser ablation:intravascular laser catheter breakage[J].BMJ Case Rep, 2013.
10. Duman E, Yildirim E, Saba T, et al.The effect of laser wavelength on postoperative pain score in the endovenous ablation of saphenous vein insufficiency[J].Diagn Interv Radiol, 2013, 19(4):326-329.
11. 龔凱, 黃道景, 張亞明, 等.腔內激光與腔內激光聯合泡沫硬化劑治療下肢靜脈曲張的比較研究[J].中國微創外科雜志, 2012, 12(7):601-603.
12. 馮蘇, 田志龍, 賈高磊, 等.限制性內翻剝脫聯合TriVex旋切及泡沫硬化劑治療下肢靜脈曲張(附132例報告)[J].中國微創外科雜志, 2014, 14(2):151-154.
13. Burihan MC.Endovenous ablation (radiofrequency and laser) and foam sclerotherapy versus conventional surgery for great saphenous vein varices[J].Sao Paulo Med J, 2014, 132(1):69.
14. Badri H, Bhattacharya V.A review of current treatment strategies for varicose veins[J].Recent Pat Cardiovasc Drug Discov, 2008, 3(2):126-136.
15. Coleridge Smith P.Sclerotherapy and foam sclerotherapy for varicose veins[J].Phlebology, 2009, 24(6):260-269.

CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

Clinical Research on Intracavity Laser Combining with Poly Cinnamyl Alcohol Foam Hardener in Treatment of Lower Extremity Varicose Veins

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